Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum.
HiTOP
anxiety disorders
clinical utility
depression
eating disorders
emotional dysfunction
internalizing
negative affect
neuroticism
sexual dysfunction
somatoform
Journal
World psychiatry : official journal of the World Psychiatric Association (WPA)
ISSN: 1723-8617
Titre abrégé: World Psychiatry
Pays: Italy
ID NLM: 101189643
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
entrez:
11
1
2022
pubmed:
12
1
2022
medline:
12
1
2022
Statut:
ppublish
Résumé
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological system that addresses shortcomings of traditional mental disorder diagnoses, including arbitrary boundaries between psychopathology and normality, frequent disorder co-occurrence, substantial heterogeneity within disorders, and diagnostic unreliability over time and across clinicians. This paper reviews evidence on the validity and utility of the internalizing and somatoform spectra of HiTOP, which together provide support for an emotional dysfunction superspectrum. These spectra are composed of homogeneous symptom and maladaptive trait dimensions currently subsumed within multiple diagnostic classes, including depressive, anxiety, trauma-related, eating, bipolar, and somatic symptom disorders, as well as sexual dysfunction and aspects of personality disorders. Dimensions falling within the emotional dysfunction superspectrum are broadly linked to individual differences in negative affect/neuroticism. Extensive evidence establishes that dimensions falling within the superspectrum share genetic diatheses, environmental risk factors, cognitive and affective difficulties, neural substrates and biomarkers, childhood temperamental antecedents, and treatment response. The structure of these validators mirrors the quantitative structure of the superspectrum, with some correlates more specific to internalizing or somatoform conditions, and others common to both, thereby underlining the hierarchical structure of the domain. Compared to traditional diagnoses, the internalizing and somatoform spectra demonstrated substantially improved utility: greater reliability, larger explanatory and predictive power, and greater clinical applicability. Validated measures are currently available to implement the HiTOP system in practice, which can make diagnostic classification more useful, both in research and in the clinic.
Identifiants
pubmed: 35015357
doi: 10.1002/wps.20943
pmc: PMC8751579
doi:
Types de publication
Journal Article
Langues
eng
Pagination
26-54Subventions
Organisme : NIMH NIH HHS
ID : R01 MH107444
Pays : United States
Investigateurs
Kamran Afzali
(K)
Marina A Bornovalova
(MA)
William T Carpenter
(WT)
Natacha Carragher
(N)
David C Cicero
(DC)
Danielle M Dick
(DM)
Anna R Docherty
(AR)
Michael B First
(MB)
Eiko I Fried
(EI)
Michael N Hallquist
(MN)
Katherine Jonas
(K)
Katherine M Keyes
(KM)
Robert D Latzman
(RD)
Kristian E Markon
(KE)
Les C Morey
(LC)
Stephanie N Mullins-Sweatt
(SN)
Kristin Naragon-Gainey
(K)
Thomas M Olino
(TM)
Praveetha Patalay
(P)
Christopher J Patrick
(CJ)
Aaron L Pincus
(AL)
Ulrich Reininghaus
(U)
Craig Rodriguez-Seijas
(C)
Lauren A Rutter
(LA)
Giovanni A Salum
(GA)
Alexander J Shackman
(AJ)
Andrew E Skodol
(AE)
Tim Slade
(T)
Kathryn Tabb
(K)
Jennifer L Tackett
(JL)
Ashley L Watts
(AL)
Amanda A Uliaszek
(AA)
Thomas A Widiger
(TA)
David H Zald
(DH)
Johannes Zimmermann
(J)
Richard E Zinbarg
(RE)
Informations de copyright
© 2022 World Psychiatric Association.
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