A method for small-area estimation of population mortality in settings affected by crises.

Crisis Death rate Displaced Emergency Humanitarian Method Mortality Predictive model Secondary data Small area estimation War

Journal

Population health metrics
ISSN: 1478-7954
Titre abrégé: Popul Health Metr
Pays: England
ID NLM: 101178411

Informations de publication

Date de publication:
11 01 2022
Historique:
received: 25 05 2021
accepted: 02 01 2022
entrez: 12 1 2022
pubmed: 13 1 2022
medline: 1 2 2022
Statut: epublish

Résumé

Populations affected by crises (armed conflict, food insecurity, natural disasters) are poorly covered by demographic surveillance. As such, crisis-wide estimation of population mortality is extremely challenging, resulting in a lack of evidence to inform humanitarian response and conflict resolution. We describe here a 'small-area estimation' method to circumvent these data gaps and quantify both total and excess (i.e. crisis-attributable) death rates and tolls, both overall and for granular geographic (e.g. district) and time (e.g. month) strata. The method is based on analysis of data previously collected by national and humanitarian actors, including ground survey observations of mortality, displacement-adjusted population denominators and datasets of variables that may predict the death rate. We describe the six sequential steps required for the method's implementation and illustrate its recent application in Somalia, South Sudan and northeast Nigeria, based on a generic set of analysis scripts. Descriptive analysis of ground survey data reveals informative patterns, e.g. concerning the contribution of injuries to overall mortality, or household net migration. Despite some data sparsity, for each crisis that we have applied the method to thus far, available predictor data allow the specification of reasonably predictive mixed effects models of crude and under 5 years death rate, validated using cross-validation. Assumptions about values of the predictors in the absence of a crisis provide counterfactual and excess mortality estimates. The method enables retrospective estimation of crisis-attributable mortality with considerable geographic and period stratification, and can therefore contribute to better understanding and historical memorialisation of the public health effects of crises. We discuss key limitations and areas for further development.

Sections du résumé

BACKGROUND
Populations affected by crises (armed conflict, food insecurity, natural disasters) are poorly covered by demographic surveillance. As such, crisis-wide estimation of population mortality is extremely challenging, resulting in a lack of evidence to inform humanitarian response and conflict resolution.
METHODS
We describe here a 'small-area estimation' method to circumvent these data gaps and quantify both total and excess (i.e. crisis-attributable) death rates and tolls, both overall and for granular geographic (e.g. district) and time (e.g. month) strata. The method is based on analysis of data previously collected by national and humanitarian actors, including ground survey observations of mortality, displacement-adjusted population denominators and datasets of variables that may predict the death rate. We describe the six sequential steps required for the method's implementation and illustrate its recent application in Somalia, South Sudan and northeast Nigeria, based on a generic set of analysis scripts.
RESULTS
Descriptive analysis of ground survey data reveals informative patterns, e.g. concerning the contribution of injuries to overall mortality, or household net migration. Despite some data sparsity, for each crisis that we have applied the method to thus far, available predictor data allow the specification of reasonably predictive mixed effects models of crude and under 5 years death rate, validated using cross-validation. Assumptions about values of the predictors in the absence of a crisis provide counterfactual and excess mortality estimates.
CONCLUSIONS
The method enables retrospective estimation of crisis-attributable mortality with considerable geographic and period stratification, and can therefore contribute to better understanding and historical memorialisation of the public health effects of crises. We discuss key limitations and areas for further development.

Identifiants

pubmed: 35016675
doi: 10.1186/s12963-022-00283-6
pii: 10.1186/s12963-022-00283-6
pmc: PMC8751462
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4

Informations de copyright

© 2022. The Author(s).

Références

Emerg Themes Epidemiol. 2007 Jun 01;4:9
pubmed: 17543103
Lancet. 2017 Nov 18;390(10109):2297-2313
pubmed: 28602558
Emerg Themes Epidemiol. 2018 May 28;15:8
pubmed: 29872451
Confl Health. 2016 Jul 20;10:15
pubmed: 27441038
Confl Health. 2019 Jan 7;13:1
pubmed: 30627212
Popul Stud (Camb). 2008 Mar;62(1):39-53
pubmed: 18278672
BMJ Glob Health. 2021 Mar;6(3):
pubmed: 33758012
Lancet. 2010 Jan 23;375(9711):294-300
pubmed: 20109956
Confl Health. 2017 Jul 3;11:12
pubmed: 28680460
Lancet. 2004 Oct 9-15;364(9442):1315-20
pubmed: 15474133
PLoS Med. 2008 Jul 1;5(7):e146
pubmed: 18597552
Epidemiology. 2019 Jul;30(4):549-552
pubmed: 30640732
Disasters. 2009 Oct;33(4):503-21
pubmed: 19500327
PLoS One. 2014 Oct 21;9(10):e109022
pubmed: 25333954
PLoS Med. 2021 May 20;18(5):e1003571
pubmed: 34014945
Popul Health Metr. 2011 Nov 09;9(1):57
pubmed: 22071133
PLoS Med. 2013 Oct;10(10):e1001533
pubmed: 24143140
Disaster Med Public Health Prep. 2009 Jun;3(2):88-96
pubmed: 19491603
J Cogn Dev. 2010;11(2):121-136
pubmed: 21743795
Int J Epidemiol. 2017 Feb 1;46(1):348-355
pubmed: 27283160
Nat Commun. 2021 Apr 22;12(1):2394
pubmed: 33888698
N Engl J Med. 2008 Jan 31;358(5):484-93
pubmed: 18184950

Auteurs

Francesco Checchi (F)

Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Francesco.checchi@lshtm.ac.uk.

Adrienne Testa (A)

Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Amy Gimma (A)

Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Emilie Koum-Besson (E)

Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Abdihamid Warsame (A)

Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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