Novel Hemostatic Gel As Rescue Therapy for Postsphincterotomy Bleeding Refractory to Self-Expanding Metallic Stent Placement.


Journal

ACG case reports journal
ISSN: 2326-3253
Titre abrégé: ACG Case Rep J
Pays: United States
ID NLM: 101638398

Informations de publication

Date de publication:
Jan 2022
Historique:
received: 09 02 2021
accepted: 18 10 2021
entrez: 12 1 2022
pubmed: 13 1 2022
medline: 13 1 2022
Statut: epublish

Résumé

Endoscopic sphincterotomy (ES) is commonly performed during endoscopic retrograde cholangiopancreatography, and bleeding is a severe adverse event. PuraStat is a peptide developed as a hemostatic agent for endoscopy. We report its use as a hemostatic strategy in post-ES bleeding refractory to combined hemostasis. A patient with choledocholithiasis underwent endoscopic retrograde cholangiopancreatography for stone removal. After the ES, severe bleeding refractory to the injection of diluted epinephrine around the bleeding source and metal stent placement occurred. Hemostasis was achieved with the application of the hemostatic gel. We reported the use of novel self-assembling hemostatic gel as an effective therapeutic tool for post-ES refractory bleeding.

Identifiants

pubmed: 35018294
doi: 10.14309/crj.0000000000000744
pii: ACGCR-21-0162
pmc: PMC8740862
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e00744

Informations de copyright

© 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.

Références

Gastrointest Endosc. 2017 Jan;85(1):32-47
pubmed: 27546389
Gastrointest Endosc. 1991 May-Jun;37(3):383-93
pubmed: 2070995
Surg Endosc. 2019 Oct;33(10):3334-3340
pubmed: 30604265
Endoscopy. 2020 Sep;52(9):773-779
pubmed: 32316041
J Clin Gastroenterol. 2010 Sep;44(8):e167-70
pubmed: 20628312
Endoscopy. 2011 Apr;43(4):369-72
pubmed: 21360425
Am J Gastroenterol. 2004 Feb;99(2):244-8
pubmed: 15046211
World J Gastroenterol. 2016 Mar 21;22(11):3196-201
pubmed: 27003996
PLoS One. 2019 Mar 12;14(3):e0212362
pubmed: 30861007
Dig Endosc. 2021 Jul;33(5):815-821
pubmed: 33010074

Auteurs

Mario Gagliardi (M)

Digestive Endoscopy Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Salerno, Italy.

Giovanni Oliviero (G)

Digestive Endoscopy Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Salerno, Italy.

Michele Fusco (M)

Digestive Endoscopy Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Salerno, Italy.

Marco Napoli (M)

Digestive Surgical Endoscopy Unit, Polyclinic "Agostino Gemelli" Foundation, Rome, Italy.

Andrea Sica (A)

Anesthesia and Intensive Care Unit, "Maurizio Bufalini Hospital," Cesena, Italy.

Attilio Maurano (A)

Digestive Endoscopy Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Salerno, Italy.

Mariano Sica (M)

Digestive Endoscopy Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Salerno, Italy.

Claudio Zulli (C)

Digestive Endoscopy Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Salerno, Italy.

Classifications MeSH