A 2-year longitudinal study of skeletal muscle mass in women over 40 years of age with degenerative lumbar scoliosis.
Bioelectrical impedance analyzer
Degenerative lumbar scoliosis
Longitudinal studies
Skeletal muscle mass
Journal
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
ISSN: 1432-0932
Titre abrégé: Eur Spine J
Pays: Germany
ID NLM: 9301980
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
received:
03
06
2021
accepted:
18
10
2021
revised:
15
08
2021
pubmed:
13
1
2022
medline:
21
5
2022
entrez:
12
1
2022
Statut:
ppublish
Résumé
We investigated changes in skeletal muscle mass and bone mineral density in degenerative lumbar scoliosis (DLS) patients during a 2-year follow-up following diagnosis. This study included 418 Japanese women, identifying 50 patients for the DLS group (mean age 76.4 years) and 368 patients for the control group (mean age 73.4 years). Whole-body skeletal muscle mass was measured using a Bioelectrical Impedance Analyzer. Bone mineral density (BMD) was measured using DXA. Skin autofluorescence (SAF), a marker of advanced glycation end products in the skin, was measured using a spectroscope. Spinal alignment, skeletal muscle mass, BMD, grip strength, and SAF were examined and the amount of change 1 and 2 years from the initial examination for each item was compared between groups. Height, body fat mass, grip strength, upper limb muscle mass, and trunk muscle mass in the DLS group were significantly lower, and lumbar spine BMD was significantly greater compared to controls at the first visit (p < 0.05). There was no significant difference in spinal alignment in the DLS group after 2 years compared with baseline. Trunk muscle mass also decreased significantly more in the DLS group (-2.7%) than in the control group (-1.1%) over the 2-year follow-up (p < 0.05). In this study, trunk muscle mass in the DLS group decreased about 2.4 times more in 2 years compared with the control group (p < 0.05). It may be possible to clarify the mechanism of kyphoscoliosis progression in the future with large-scale longitudinal studies.
Identifiants
pubmed: 35020079
doi: 10.1007/s00586-021-07038-1
pii: 10.1007/s00586-021-07038-1
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1158-1165Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
World Health Organisation (2018) Ageing and Health, https:// www.who.int/news-room/fact-sheets/detail/ageing-and-health . Accessed 23 Jan 2019
Takemitsu Y, Harada Y, Iwahara T, Miyamoto M, Miyatake Y (1988) Lumbar degenerative kyphosis. clinical, radiological and epidemiological studie (Phila Pa 1976). Spine. 13(11):1317–26
doi: 10.1097/00007632-198811000-00019
Aebi M (2005) The adult scoliosis. Eur Spine J 14(10):925–948
doi: 10.1007/s00586-005-1053-9
Glassman SD, Bridwell K, Dimar JR, Horton W, Berven S, Schwab F (2005) The impact of positive sagittal balance in adult spinal deformity. Spine 30(18):2024–2029
doi: 10.1097/01.brs.0000179086.30449.96
Lafage V, Schwab F, Patel A, Hawkinson N, Farcy JP (2009) Pelvic tilt and truncal inclination: two key radiographic parameters in the setting of adults with spinal deformity. Spine 34(17):E599-606
doi: 10.1097/BRS.0b013e3181aad219
Schwab F, Ungar B, Blondel B, Buchowski J, Coe J, Deinlein D, DeWald C, Mehdian H, Shaffrey C, Tribus C, Lafage V (2012) Scoliosis research society-schwab adult spinal deformity classification: a validation study. Spine 37(12):1077–1082
doi: 10.1097/BRS.0b013e31823e15e2
Ploumis A, Liu H, Mehbod AA, Transfeldt EE, Winter RB (2009) A Correlation of radiographic and functional measurements in adult degenerative scoliosis. Spine 34(15):1581–1584
doi: 10.1097/BRS.0b013e31819c94cc
Saito M, Marumo K (2010) Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos Int 21(2):195–214
doi: 10.1007/s00198-009-1066-z
Pokharna HK, Phillips FM (1998) Collagen crosslinks in human lumbar intervertebral disc aging. Spine 23(15):1645–1648
doi: 10.1097/00007632-199808010-00005
Duance VC, Crean JK, Sims TJ, Avery N, Smith S, Menage J, Eisenstein SM, Roberts S (1998) Changes in collagen cross-linking in degenerative disc disease and scoliosis. Spine 23(23):2545–2551
doi: 10.1097/00007632-199812010-00009
Haus JM, Carrithers JA, Trappe SW, Trappe TA (2007) Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle. J Appl Physiol (1985). 103(6):2068–2076
doi: 10.1152/japplphysiol.00670.2007
Eguchi Y, Toyoguchi T, Inage K, Fujimoto K, Orita S, Yamauchi K, Suzuki M, Kanamoto H, Abe K, Norimoto M, Umimura T, Koda M, Furuya T, Aoki Y, Takahashi K, Ohtori S (2018) Pentosidine concentration is associated with degenerative lumbar scoliosis in older women: preliminary results. Eur Spine J 27:597–606
doi: 10.1007/s00586-017-5370-6
Meerwaldt R, Hartog JW, Graaff R, Huisman RJ, Links TP, den Hollander NC, Thorpe SR, Baynes JW, Navis G, Gans RO, Smit AJ (2005) Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients. J Am Soc Nephrol 16(12):3687–3693
doi: 10.1681/ASN.2005020144
Eguchi Y, Toyoguchi T, Inage K, Fujimoto K, Orita S, Suzuki M, Kanamoto H, Abe K, Norimoto M, Umimura T, Sato T, Koda M, Furuya T, Aoki Y, Nakamura J, Akazawa T, Takahashi K, Ohtori S (2019) Analysis of skeletal muscle mass in women over 40 with degenerative lumbar scoliosis. Eur Spine J 28(7):1618–1625
doi: 10.1007/s00586-018-5845-0
Yagi M, Hosogane N, Watanabe K, Asazuma T, Matsumoto M; Keio Spine Research Group (2016) The paravertebral muscle and psoas for the maintenance of global spinal alignment in patient with degenerative lumbar scoliosis. Spine J 16(4):451–458
doi: 10.1016/j.spinee.2015.07.001
Hori Y, Hoshino M, Inage K, Miyagi M, Takahashi S, Ohyama S, Suzuki A, Tsujio T, Terai H, Dohzono S, Sasaoka R, Toyoda H, Kato M, Matsumura A, Namikawa T, Seki M, Yamada K, Habibi H, Salimi H, Yamashita M, Yamauchi T, Furuya T, Orita S, Maki S, Shiga Y, Inoue M, Inoue G, Fujimaki H, Murata K, Kawakubo A, Kabata D, Shintani A, Ohtori S, Takaso M, Nakamura H (2019) ISSLS Prize in clinical science 2019: clinical importance of trunk muscle mass for low back pain, spinal balance, and quality of life-a multicenter cross-sectional study. Eur Spine J 28(5):914–921
doi: 10.1007/s00586-019-05904-7
Eguchi Y, Toyoguchi T, Inage K, Fujimoto K, Orita S, Suzuki M, Kanamoto H, Abe K, Norimoto M, Umimura T, Koda M, Furuya T, Aoki Y, Nakamura J, Akazawa T, Takahashi K, Ohtori S (2019) Advanced glycation end products are associated with sarcopenia in older women: aging marker dynamics. J Women Aging. 33:1–13
Kang CH, Shin MJ, Kim SM, Lee SH, Lee CS (2007) MRI of paraspinal muscles in lumbar degenerative kyphosis patients and control patients with chronic low back pain. Clin Radiol 62(5):479–486
doi: 10.1016/j.crad.2006.12.002
Shafaq N, Suzuki A, Matsumura A, Terai H, Toyoda H, Yasuda H, Ibrahim M, Nakamura H (2012) Asymmetric degeneration of paravertebral muscles in patients with degenerative lumbar scoliosis. Spine 37(16):1398–1406
doi: 10.1097/BRS.0b013e31824c767e
Xie D, Zhang J, Ding W, Yang S, Yang D, Ma L, Zhang J (2019) Abnormal change of paravertebral muscle in adult degenerative scoliosis and its association with bony structural parameters. Eur Spine J 28(7):1626–1637
doi: 10.1007/s00586-019-05958-7
Kim H, Lee CK, Yeom JS, Lee JH, Cho JH, Shin SI, Lee HJ, Chang BS (2013) Asymmetry of the cross-sectional area of paravertebral and psoas muscle in patients with degenerative scoliosis. Eur Spine J 22(6):1332–1338
doi: 10.1007/s00586-013-2740-6
Enomoto M, Ukegawa D, Sakaki K, Tomizawa S, Arai Y, Kawabata S, Kato T, Yoshii T, Shinomiya K, Okawa A (2012) Increase in paravertebral muscle activity in lumbar kyphosis patients by surface electromyography compared with lumbar spinal canal stenosis patients and healthy volunteers. J Spinal Disord Tech 25(6):E167–E173
doi: 10.1097/BSD.0b013e31825d63c4
Liu G, Peacock M, Eilam O, Dorulla G, Braunstein E, Johnston CC (1997) Effect of osteoarthritis in the lumbar spine and hip on bone mineral density and diagnosis of osteoporosis in elderly men and women. Osteoporos Int 7(6):564–569
doi: 10.1007/BF02652563