Hierarchical Self-Assembly Pathways of Peptoid Helices and Sheets.
Journal
Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849
Informations de publication
Date de publication:
14 03 2022
14 03 2022
Historique:
pubmed:
13
1
2022
medline:
16
4
2022
entrez:
12
1
2022
Statut:
ppublish
Résumé
Peptoids (N-substituted glycines) are a class of tailorable synthetic peptidomic polymers. Amphiphilic diblock peptoids have been engineered to assemble 2D crystalline lattices with applications in catalysis and molecular separations. Assembly is induced in an organic solvent/water mixture by evaporating the organic phase, but the assembly pathways remain uncharacterized. We conduct all-atom molecular dynamics simulations of Nbrpe6Nc6 as a prototypical amphiphilic diblock peptoid comprising an NH
Identifiants
pubmed: 35020390
doi: 10.1021/acs.biomac.1c01385
doi:
Substances chimiques
N-substituted Glycines
0
Peptoids
0
Polymers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM