Arterial intracranial thrombosis as the first manifestation of vaccine-induced immune thrombotic thrombocytopenia (VITT): a case report.
COVID-19
Stroke
Thrombocytopenia
VITT
Vaccine
Journal
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
21
10
2021
accepted:
02
12
2021
pubmed:
14
1
2022
medline:
24
2
2022
entrez:
13
1
2022
Statut:
ppublish
Résumé
We describe a severe case of vaccine-induced immune thrombotic thrombocytopenia (VITT) after the first dose of the ChAdOx1 nCoV-19 vaccine leading to massive ischemic stroke. A 42-year-old woman developed acute left hemiparesis (NIHSS 12) 9 days after the first vaccine dose. The blood tests revealed low platelets (70 10 Healthcare providers should be aware of the possibility of ischemic stroke as a manifestation of VITT. Awareness on this very rare and possibly fatal complication should be reinforced on both the vaccine recipients and general practitioners.
Identifiants
pubmed: 35022931
doi: 10.1007/s10072-021-05800-3
pii: 10.1007/s10072-021-05800-3
pmc: PMC8754523
doi:
Substances chimiques
COVID-19 Vaccines
0
Vaccines
0
ChAdOx1 nCoV-19
B5S3K2V0G8
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2085-2089Informations de copyright
© 2021. Fondazione Società Italiana di Neurologia.
Références
J Biomed Sci. 2020 Dec 20;27(1):104
pubmed: 33341119
Neurology. 2021 Jul 26;:
pubmed: 34312301
Nat Commun. 2021 Aug 2;12(1):4663
pubmed: 34341358
Lancet Haematol. 2022 Jan;9(1):e73-e80
pubmed: 34774202
JAMA Neurol. 2021 Nov 1;78(11):1314-1323
pubmed: 34581763
J Neurol Neurosurg Psychiatry. 2021 Nov;92(11):1247-1248
pubmed: 34035134
Ann Neurol. 2021 Oct;90(4):627-639
pubmed: 34288044
Eur J Neurol. 2021 Nov;28(11):3656-3662
pubmed: 34293217
N Engl J Med. 2021 Jun 10;384(23):2254-2256
pubmed: 33861524
Blood Transfus. 2021 Jul;19(4):281-283
pubmed: 33871350
BMJ Case Rep. 2021 Jul 13;14(7):
pubmed: 34257129
J Stroke Cerebrovasc Dis. 2021 Nov;30(11):106072
pubmed: 34461442
Blood Adv. 2021 Jun 22;5(12):2569-2574
pubmed: 34137813
Ann Vasc Surg. 2022 Feb;79:438.e1-438.e4
pubmed: 34644642