Developing Treatments for Alzheimer's and Related Disorders with Precision Medicine: A Vision.

Alzheimer Disease / diagnosis Humans Precision Medicine
Alzheimer’s Precision medicine treatments

Journal

Advances in experimental medicine and biology
ISSN: 0065-2598
Titre abrégé: Adv Exp Med Biol
Pays: United States
ID NLM: 0121103

Informations de publication

Date de publication:
2021
Historique:
entrez: 13 1 2022
pubmed: 14 1 2022
medline: 15 1 2022
Statut: ppublish

Résumé

Precision medicine, also known as personalized medicine, is concerned with finding the right treatment for the right patient at the right time. It is a way of thinking focused on parsing heterogeneity ultimately down to the level of the individual. Its main mission is to identify characteristics of heterogeneous clinical conditions so as to target tailored therapies to individuals. Precision Medicine however is not an agnostic collection of all manner of clinical, genetic and other biologic data in select cohorts. This is an important point. Simply collecting as much information as possible on individuals without applying this way of thinking should not be considered Precision Medicine.

Identifiants

DOI: 10.1007/978-3-030-78787-5_49 PMID: 35023131 PMC: PMC9358929
pubmed: 35023131
doi: 10.1007/978-3-030-78787-5_49
pmc: PMC9358929
mid: NIHMS1827918
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

395-402

Subventions

Organisme : NIA NIH HHS
ID : P30 AG066507
Pays : United States
Organisme : Intramural NIH HHS
ID : Z99 AG999999
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA AG000975
Pays : United States

Informations de copyright

© 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.

Références

Alzheimers Dement. 2019 Aug;15(8):1071-1080
pubmed: 31422798
Acta Neuropathol. 2019 Aug;138(2):221-236
pubmed: 30982098
BMJ. 2021 Feb 25;372:n156
pubmed: 33632704
Am J Geriatr Psychiatry. 2014 Apr;22(4):398-414
pubmed: 24502822
Lancet. 2017 Dec 16;390(10113):2673-2734
pubmed: 28735855
Alzheimers Dement (Amst). 2019 Apr 18;11:333-339
pubmed: 31024987
J Alzheimers Dis. 2018;66(1):97-104
pubmed: 30198872
PLoS One. 2018 Sep 25;13(9):e0204695
pubmed: 30252906

Auteurs

Dimitrios Avramopoulos (D)

Department of Genetic Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Dimitrios Kapogiannis (D)

Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Intramural Research Program, National Institute on Aging (NIA/NIH), Baltimore, MD, USA.

Jeannie-Marie Leoutsakos (JM)

Departments of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Constantine G Lyketsos (CG)

Departments of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. kostas@jhmi.edu.

Vasiliki Mahairaki (V)

Department of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Milap Nowrangi (M)

Departments of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Kenichi Oishi (K)

Departments of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Esther S Oh (ES)

Departments of Medicine (Geriatric Medicine and Gerontology), School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Paul B Rosenberg (PB)

Departments of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Quincy Samus (Q)

Departments of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Gwenn S Smith (GS)

Departments of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Kenneth Witwer (K)

Departments of Molecular and Comparative Pathobiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Sevil Yasar (S)

Departments of Medicine (Geriatric Medicine and Gerontology), School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Peter P Zandi (PP)

Departments of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › Developing Treatments for Alzheimer's and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Developing Treatments for Alzheimer's and...
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Developing Treatments for Alzheimer's and...