Nuclear Expression of Pygo2 Correlates with Poorly Differentiated State Involving c-Myc, PCNA and Bcl9 in Myanmar Hepatocellular Carcinoma.
Bcl9
Myanmar hepatocellular carcinoma
PCNA
Pygo2
c-Myc
Journal
Acta histochemica et cytochemica
ISSN: 0044-5991
Titre abrégé: Acta Histochem Cytochem
Pays: Japan
ID NLM: 0147110
Informations de publication
Date de publication:
24 Dec 2021
24 Dec 2021
Historique:
received:
29
10
2021
accepted:
03
12
2021
entrez:
13
1
2022
pubmed:
14
1
2022
medline:
14
1
2022
Statut:
ppublish
Résumé
In Myanmar, hepatocellular carcinoma (HCC) is commonly seen in young adult and associated with poor prognosis, while the molecular mechanisms that characterize HCC in Myanmar are unknown. As co-activation of Wnt/β-catenin signaling and c-Myc (Myc) are reported to associate with malignancy of HCC, we immunohistochemically investigated the expression of Pygo2 and Bcl9, the co-activators of the Wnt/β-catenin signaling, Myc and PCNA in 60 cases of Myanmar HCC. Pygo2 expression was confirmed by
Identifiants
pubmed: 35023882
doi: 10.1267/ahc.21-00090
pii: JST.JSTAGE/ahc/21-00090
pmc: PMC8727843
doi:
Types de publication
Journal Article
Langues
eng
Pagination
195-206Informations de copyright
2021 The Japan Society of Histochemistry and Cytochemistry.
Déclaration de conflit d'intérêts
VThe authors declare no conflict of interest.
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