Prescribing Pattern of Dermatological Compounding in Ethiopia: The Case of ALERT Hospital.
ALERT hospital
compounding
dermatological preparations
prescription pattern
Journal
Integrated pharmacy research & practice
ISSN: 2230-5254
Titre abrégé: Integr Pharm Res Pract
Pays: New Zealand
ID NLM: 101656778
Informations de publication
Date de publication:
2022
2022
Historique:
received:
03
11
2021
accepted:
21
12
2021
entrez:
13
1
2022
pubmed:
14
1
2022
medline:
14
1
2022
Statut:
epublish
Résumé
Skin diseases are among the major contributors of disease burden in Ethiopia affecting individuals of all age. Extemporaneous compounding of topical medications serves as a necessary option to treat skin diseases when manufactured medications could not meet specific patient needs. Different classes of drugs are commonly used for the treatment of dermatologic diseases. Failure to periodically assess the prescribing pattern and patient needs may lead to inappropriate planning and implementation that ultimately compromise the service. Periodic prescription analysis for compounded medications helps to monitor the prescription pattern with respect to medication selection, disease condition, dosage form types and other relevant parameters. The current study was conducted to analyze the pattern of compounding prescriptions for dermatologicals in ALERT hospital. A cross-sectional design was conducted by retrospectively evaluating compounding prescription records of January and July, 2021. A total of 460 prescriptions in the hospital community pharmacy were systematically selected. Data related to disease pattern, product selection and dosage form type were extracted and analyzed. Data analysis was done using software for the statistical package for social science version 25.0. A total of 441 prescriptions containing dermatological products for compounding were analyzed. Most patients were female (62.8%) and aged 30-64 years (44.0%). Psoriasis (36.2%), acne vulgaris (15.3%), and rosacea (13.4%) were the top 3 skin diseases for which the compounding preparations were prescribed. Salicylic acid (38.0%) was the most frequently prescribed drug followed by betamethasone (20.2%); while white petrolatum (47.2%) was the most common diluting agent used for compounding. Psoriasis was the major dermatologic disease for compounding prescriptions and salicylic acid was the most frequent product used in compounding for treatment of the prescribed skin diseases.
Sections du résumé
BACKGROUND
BACKGROUND
Skin diseases are among the major contributors of disease burden in Ethiopia affecting individuals of all age. Extemporaneous compounding of topical medications serves as a necessary option to treat skin diseases when manufactured medications could not meet specific patient needs. Different classes of drugs are commonly used for the treatment of dermatologic diseases. Failure to periodically assess the prescribing pattern and patient needs may lead to inappropriate planning and implementation that ultimately compromise the service. Periodic prescription analysis for compounded medications helps to monitor the prescription pattern with respect to medication selection, disease condition, dosage form types and other relevant parameters. The current study was conducted to analyze the pattern of compounding prescriptions for dermatologicals in ALERT hospital.
METHODS
METHODS
A cross-sectional design was conducted by retrospectively evaluating compounding prescription records of January and July, 2021. A total of 460 prescriptions in the hospital community pharmacy were systematically selected. Data related to disease pattern, product selection and dosage form type were extracted and analyzed. Data analysis was done using software for the statistical package for social science version 25.0.
RESULTS
RESULTS
A total of 441 prescriptions containing dermatological products for compounding were analyzed. Most patients were female (62.8%) and aged 30-64 years (44.0%). Psoriasis (36.2%), acne vulgaris (15.3%), and rosacea (13.4%) were the top 3 skin diseases for which the compounding preparations were prescribed. Salicylic acid (38.0%) was the most frequently prescribed drug followed by betamethasone (20.2%); while white petrolatum (47.2%) was the most common diluting agent used for compounding.
CONCLUSION
CONCLUSIONS
Psoriasis was the major dermatologic disease for compounding prescriptions and salicylic acid was the most frequent product used in compounding for treatment of the prescribed skin diseases.
Identifiants
pubmed: 35024353
doi: 10.2147/IPRP.S346395
pii: 346395
pmc: PMC8747791
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1-8Informations de copyright
© 2022 Selam et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Int J Pharm Compd. 2016 Nov-Dec;20(6):461-467
pubmed: 28339384
Dermatol Clin. 1998 Apr;16(2):321-7
pubmed: 9589205
J Invest Dermatol. 2014 Jun;134(6):1527-1534
pubmed: 24166134
J Pain Palliat Care Pharmacother. 2002;16(4):71-8
pubmed: 14635828
Acta Paediatr. 2003 Apr;92(4):486-90
pubmed: 12801118
Minerva Pediatr. 2011 Aug;63(4):293-304
pubmed: 21909065
Am J Health Syst Pharm. 2013 Aug 15;70(16):1414-27
pubmed: 23903480
Drugs R D. 2013 Mar;13(1):1-8
pubmed: 23526368
Risk Manag Healthc Policy. 2021 May 12;14:1933-1938
pubmed: 34012305
BMJ. 2012 Nov 05;345:e7432
pubmed: 23129491
J Am Acad Dermatol. 2008 Jan;58(1):56-9
pubmed: 17945383
BMC Pediatr. 2013 May 21;13:81
pubmed: 23688279
J Dtsch Dermatol Ges. 2012 Feb;10(2):103-9
pubmed: 21851553
Adv Dermatol. 1992;7:231-52; discussion 253
pubmed: 1739582
J Drugs Dermatol. 2018 Jul 1;17(7):s17-s22
pubmed: 30005109
Pharm World Sci. 2003 Dec;25(6):280-7
pubmed: 14689817