A Rare Case of Pituitary Carcinoma With Bone Metastases: 68Ga-DOTATATE PET/CT Findings.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
01 Mar 2022
01 Mar 2022
Historique:
pubmed:
14
1
2022
medline:
4
2
2022
entrez:
13
1
2022
Statut:
ppublish
Résumé
Pituitary carcinomas are extremely rare and aggressive tumors that comprise only 0.2% of all pituitary tumors. Because of its rarity, pituitary carcinomas are difficult to diagnose. Conventional imaging methods are inadequate to detect metastatic lesions. Pituitary carcinomas are neuroendocrine tumors and express somatostatin receptors; therefore, 68Ga-DOTATATE PET/CT may be used in the staging of these rare tumors. Herein, we present an exceptional case of pituitary carcinoma with sclerotic skeletal metastases showing 68Ga-DOTATATE uptake.
Identifiants
pubmed: 35025796
doi: 10.1097/RLU.0000000000004029
pii: 00003072-202203000-00054
doi:
Substances chimiques
Organometallic Compounds
0
Receptors, Somatostatin
0
copper dotatate CU-64
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e298-e299Informations de copyright
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: none declared.
Références
Yoo F, Kuan EC, Heaney AP, et al. Corticotrophic pituitary carcinoma with cervical metastases: case series and literature review. Pituitary . 2018;21:290–301.
Soon WC, Czyz M, Dhir J. Metastatic pituitary carcinoma causing cord compression. World Neurosurg . 2020;139:266–267.
Lenders N, McCormack A. Malignant transformation in non-functioning pituitary adenomas (pituitary carcinoma). Pituitary . 2018;21:217–229.
Srirajaskanthan R, Kayani I, Quigley AM, et al. The role of 68 Ga-DOTATATE PET in patients with neuroendocrine tumors and negative or equivocal findings on 111 In-DTPA-octreotide scintigraphy. J Nucl Med . 2010;51:875–882.
Novruzov F, Aliyev JA, Jaunmuktane Z, et al. The use of (68) Ga DOTATATE PET/CT for diagnostic assessment and monitoring of (177) Lu DOTATATE therapy in pituitary carcinoma. Clin Nucl Med . 2015;40:47–49.
Lybik N, Wale DJ, Wong KK, et al. 68 Ga-DOTATATE PET/CT imaging of refractory pituitary macroadenoma invading the orbit. Clin Nucl Med . 2021;46:505–506.
Garmes HM, Carvalheira JBC, Reis F, et al. Pituitary carcinoma: a case report and discussion of potential value of combined use of Ga-68 DOTATATE and F-18 FDG PET/CT scan to better choose therapy. Surg Neurol Int . 2017;8:162.
Xiao J, Zhu Z, Zhong D, et al. Improvement in diagnosis of metastatic pituitary carcinoma by 68 Ga DOTATATE PET/CT. Clin Nucl Med . 2015;40:e129–e131.