Potential therapeutic options for COVID-19: an update on current evidence.
Antibodies, Monoclonal
/ therapeutic use
Antibodies, Neutralizing
Antiviral Agents
/ therapeutic use
COVID-19
/ therapy
Clinical Trials as Topic
Dietary Supplements
Humans
Immunization, Passive
/ methods
Immunoglobulins, Intravenous
/ therapeutic use
Pandemics
SARS-CoV-2
Treatment Outcome
COVID-19 Drug Treatment
COVID-19 Serotherapy
COVID-19
Cell therapy
Convalescent plasma
Immunoglobulins
Monoclonal antibodies
Repurposed drugs
Journal
European journal of medical research
ISSN: 2047-783X
Titre abrégé: Eur J Med Res
Pays: England
ID NLM: 9517857
Informations de publication
Date de publication:
13 Jan 2022
13 Jan 2022
Historique:
received:
02
10
2021
accepted:
23
12
2021
entrez:
14
1
2022
pubmed:
15
1
2022
medline:
27
1
2022
Statut:
epublish
Résumé
SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19 pandemic and is a major public health concern nowadays. The rapid and global spread of this coronavirus leads to an increase in hospitalizations and thousands of deaths in many countries. To date, great efforts have been made worldwide for the efficient management of this crisis, but there is still no effective and specific treatment for COVID-19. The primary therapies to treat the disease are antivirals, anti-inflammatories and respiratory therapy. In addition, antibody therapies currently have been a many active and essential part of SARS-CoV-2 infection treatment. Ongoing trials are proposed different therapeutic options including various drugs, convalescent plasma therapy, monoclonal antibodies, immunoglobulin therapy, and cell therapy. The present study summarized current evidence of these therapeutic approaches to assess their efficacy and safety for COVID-19 treatment. We tried to provide comprehensive information about the available potential therapeutic approaches against COVID-19 to support researchers and physicians in any current and future progress in treating COVID-19 patients.
Identifiants
pubmed: 35027080
doi: 10.1186/s40001-021-00626-3
pii: 10.1186/s40001-021-00626-3
pmc: PMC8755901
doi:
Substances chimiques
Antibodies, Monoclonal
0
Antibodies, Neutralizing
0
Antiviral Agents
0
Immunoglobulins, Intravenous
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
6Informations de copyright
© 2022. The Author(s).
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