4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations.

Drugs Musculoskeletal medicine

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
21 Jan 2022
Historique:
received: 13 07 2021
revised: 06 10 2021
accepted: 15 12 2021
entrez: 14 1 2022
pubmed: 15 1 2022
medline: 15 1 2022
Statut: epublish

Résumé

Dysferlinopathies are muscular dystrophies caused by recessive loss-of-function mutations in dysferlin (

Identifiants

pubmed: 35028538
doi: 10.1016/j.isci.2021.103667
pii: S2589-0042(21)01637-0
pmc: PMC8741482
doi:

Types de publication

Journal Article

Langues

eng

Pagination

103667

Informations de copyright

© 2021 The Author(s).

Déclaration de conflit d'intérêts

L.P.G. is a founder of Elysium Health and Galilei Biosciences.

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Auteurs

Kana Tominaga (K)

Paul F. Glenn Center for Biology of Aging, Department of Biology, Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Department of Pathology and Oncology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyoku, Tokyo 113-8421, Japan.

Naoomi Tominaga (N)

Paul F. Glenn Center for Biology of Aging, Department of Biology, Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Eric O Williams (EO)

Paul F. Glenn Center for Biology of Aging, Department of Biology, Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Fitchburg State University, School of Heath and Natural Sciences, Antonucci Science Complex 235, Fitchburg, MA 01420, USA.

Laura Rufibach (L)

Jain Foundation, 9706 4th Avenue NE, Suite 101, Seattle, WA 98115, USA.

Verena Schöwel (V)

Muscle Research Unit, Experimental and Clinical Research Center (ECRC), a joint cooperation of Charité Universitätsmedizin Berlin and Max-Delbrück Center for Molecular Medicine, Berlin, Germany.

Simone Spuler (S)

Muscle Research Unit, Experimental and Clinical Research Center (ECRC), a joint cooperation of Charité Universitätsmedizin Berlin and Max-Delbrück Center for Molecular Medicine, Berlin, Germany.

Mohan Viswanathan (M)

Paul F. Glenn Center for Biology of Aging, Department of Biology, Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Leonard P Guarente (LP)

Paul F. Glenn Center for Biology of Aging, Department of Biology, Koch Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Classifications MeSH