Combining vascular and nerve fiber layer thickness measurements to model glaucomatous focal visual field loss.
glaucoma
optical coherence tomography angiography
retinal nerve fiber layer
structure-function correlation
visual field
Journal
Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858
Informations de publication
Date de publication:
05 2022
05 2022
Historique:
revised:
01
11
2021
received:
30
07
2021
accepted:
12
11
2021
pubmed:
15
1
2022
medline:
20
5
2022
entrez:
14
1
2022
Statut:
ppublish
Résumé
We compare the focal structure-function correlation of structural measurements of peripapillary retinal nerve fiber layer thickness (RNFL-T) using optical coherence tomography (OCT), capillary density (CD) measurements using OCT-angiography (OCT-A), or a combination of both, with visual field deviation (VFD) in early to advanced glaucoma. Primary open angle glaucoma patients (n = 46, mean ± SD age: 67 ± 10 years; VF mean deviation: -10.41 ± 6.76 dB) were included in this cross-sectional study. We performed 30-2 standard automated perimetry OCT (3.5-mm diameter ring scan) and 15°×15° OCT-A (superficial vascular complex slab). Based on a nerve fiber trajectory model, each VF test spot was assigned to an OCT-A wedge and an OCT ring-sector. Two univariate linear models (M
Identifiants
pubmed: 35029314
doi: 10.1111/nyas.14732
pmc: PMC9305098
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
133-141Informations de copyright
© 2022 The Authors. Annals of the New York Academy of Sciences published by Wiley Periodicals LLC on behalf of New York Academy of Sciences.
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