Recovery of dialysis patients with COVID-19: health outcomes 3 months after diagnosis in ERACODA.
COVID-19
dialysis
functional health status
mental health status
survival
Journal
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
ISSN: 1460-2385
Titre abrégé: Nephrol Dial Transplant
Pays: England
ID NLM: 8706402
Informations de publication
Date de publication:
25 05 2022
25 05 2022
Historique:
received:
09
11
2021
pubmed:
15
1
2022
medline:
27
5
2022
entrez:
14
1
2022
Statut:
ppublish
Résumé
Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis. We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8-6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.
Sections du résumé
BACKGROUND
Coronavirus disease 2019 (COVID-19)-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients 3 months after their COVID-19 diagnosis.
METHODS
We analyzed data on dialysis patients diagnosed with COVID-19 from 1 February 2020 to 31 March 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residence and functional and mental health status (estimated by their treating physician) 3 months after COVID-19 diagnosis. Complete follow-up data were available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression.
RESULTS
In 2449 hemodialysis patients (mean ± SD age 67.5 ± 14.4 years, 62% male), survival probabilities at 3 months after COVID-19 diagnosis were 90% for nonhospitalized patients (n = 1087), 73% for patients admitted to the hospital but not to an intensive care unit (ICU) (n = 1165) and 40% for those admitted to an ICU (n = 197). Patient survival hardly decreased between 28 days and 3 months after COVID-19 diagnosis. At 3 months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (0.8-6.3%) or a nursing home (∼5%). A higher age and frailty score at presentation and ICU admission were associated with worse functional outcome.
CONCLUSIONS
Mortality between 28 days and 3 months after COVID-19 diagnosis was low and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at 3 months after diagnosis.
Identifiants
pubmed: 35030246
pii: 6507563
doi: 10.1093/ndt/gfac008
pmc: PMC8807277
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1140-1151Investigateurs
Jeroen B van der Net
(JB)
Marie Essig
(M)
Peggy W G du Buf-Vereijken
(PWG)
Betty van Ginneken
(B)
Nanda Maas
(N)
Brigit C van Jaarsveld
(BC)
Frederike J Bemelman
(FJ)
Farah Klingenberg-Salahova
(F)
Frederiek Heenan-Vos
(F)
Marc G Vervloet
(MG)
Azam Nurmohamed
(A)
Daniel Abramowicz
(D)
Sabine Verhofstede
(S)
Omar Maoujoud
(O)
Thomas Malfait
(T)
Jana Fialova
(J)
Edoardo Melilli
(E)
Alexandre Favà
(A)
Josep M Cruzado
(JM)
Nuria Montero Perez
(NM)
Joy Lips
(J)
Harmen Krepel
(H)
Harun Adilovic
(H)
Maaike Hengst
(M)
Constantijn J A M Konings
(CJAM)
Philippe Braconnier
(P)
Daniel Weis
(D)
Ryszard Gellert
(R)
Daniela G Alferes
(DG)
Daniela Radulescu
(D)
Elena V Zakharova
(EV)
Patrice Max Ambuehl
(PM)
Rebecca Guidotti
(R)
Andrea Walker
(A)
Fanny Lepeytre
(F)
Clémentine Rabaté
(C)
Guy Rostoker
(G)
Sofia Marques
(S)
Tijana Azasevac
(T)
Gordana Strazmester Majstorovic
(GS)
Dajana Katicic
(D)
Marc Ten Dam
(M)
Thilo Krüger
(T)
Szymon Brzosko
(S)
Vassilios Liakopoulos
(V)
Adriaan L Zanen
(AL)
Susan J J Logtenberg
(SJJ)
Lutz Fricke
(L)
Olexandr Kuryata
(O)
Jeroen J P Slebe
(JJP)
Samar Abd ElHafeez
(SA)
Delphine Kemlin
(D)
Jacqueline van de Wetering
(J)
Marlies E J Reinders
(MEJ)
Dennis A Hesselink
(DA)
J Kal- van Gestel
(JK)
Jaromir Eiselt
(J)
Lukas Kielberger
(L)
Hala S El-Wakil
(HS)
Martine A M Verhoeven
(MAM)
Ian Logan
(I)
Cristina Canal
(C)
Carme Facundo
(C)
Ana M Ramos
(AM)
Alicja Debska-Slizien
(A)
Nicoline M H Veldhuizen
(NMH)
Eirini Tigka
(E)
Maria Anna Polyzou Konsta
(MAP)
Stylianos Panagoutsos
(S)
Adele Postorino
(A)
Francesco Cambareri
(F)
Irina Matceac
(I)
Ionut Nistor
(I)
Adrian Covic
(A)
J H M Groeneveld
(JHM)
Jolanda Jousma
(J)
Marjolijn van Buren
(M)
Fritz Diekmann
(F)
Federico Oppenheimer
(F)
Miquel Blasco
(M)
Tiago Assis Pereira
(TA)
Augusto Cesar Soares Dos Santos
(AC)
Carlos Arias-Cabrales
(C)
Marta Crespo
(M)
Laura Llinàs-Mallol
(L)
Anna Buxeda
(A)
Carla Burballa Tàrrega
(CB)
Dolores Redondo-Pachon
(D)
Maria Dolores Arenas Jimenez
(MDA)
Alberto Mendoza-Valderrey
(A)
Ana Cristina Martins
(AC)
Catarina Mateus
(C)
Goncalo Alvila
(G)
Ivo Laranjinha
(I)
Julia M Hofstra
(JM)
Machiel A Siezenga
(MA)
Antonio Franco
(A)
Sandra Castellano
(S)
Maria Luisa Rodríguez-Ferrero
(ML)
Sagrario Balda Manzanos
(SB)
R Haridian Sosa Barrios
(RHS)
Wim Lemahieu
(W)
Karlijn Bartelet
(K)
Ahmet Burak Dirim
(AB)
Erol Demir
(E)
Mehmet Sukru Sever
(MS)
Aydin Turkmen
(A)
Seda Şafak
(S)
Daan A M J Hollander
(DAMJ)
Angele Kerckhoffs
(A)
Stefan Büttner
(S)
Aiko P J de Vries
(APJ)
Soufian Meziyerh
(S)
Danny van der Helm
(D)
Marko Mallat
(M)
Hanneke Bouwsma
(H)
Kristina Petruliene
(K)
Iris Verberk
(I)
Frank M van der Sande
(FM)
Maarten H L Christiaans
(MHL)
Mohan Kumar N
(M)
Marina Di Luca
(MD)
Serhan Z Tuğlular
(SZ)
Andrea Kramer
(A)
Charles Beerenhout
(C)
Peter T Luik
(PT)
Julia Kerschbaum
(J)
Martin Tiefenthaler
(M)
Bruno Watschinger
(B)
Aaltje Y Adema
(AY)
Vadim A Stepanov
(VA)
Alexey B Zulkarnaev
(AB)
Kultigin Turkmen
(K)
Ilaria Gandolfini
(I)
Umberto Maggiore
(U)
Anselm Fliedner
(A)
Anders Åsberg
(A)
Geir Mjoen
(G)
Hitoshi Miyasato
(H)
Carola W H de Fijter
(CWH)
Nicola Mongera
(N)
Stefano Pini
(S)
Consuelo de Biase
(C)
Anne Els van de Logt
(A)
Rutger Maas
(R)
Olga Lebedeva
(O)
Veronica Lopez
(V)
Louis J M Reichert
(LJM)
Jacobien Verhave
(J)
Denis Titov
(D)
Ekaterina V Parshina
(EV)
Luca Zanoli
(L)
Carmelita Marcantoni
(C)
Gijs van Kempen
(G)
Liesbeth E A van Gils-Verrij
(LEA)
John C Harty
(JC)
Marleen Meurs
(M)
Marek Myslak
(M)
Paolo Lentini
(P)
Edwin den Deurwaarder
(E)
Maria Stendahl
(M)
Hormat Rahimzadeh
(H)
Marcel Schouten
(M)
Ivan Rychlik
(I)
Carlos J Cabezas-Reina
(CJ)
Ana Maria Roca
(AM)
Ferdau Nauta
(F)
İdris Sahin
(İ)
Eric Goffin
(E)
Nada Kanaan
(N)
Laura Labriola
(L)
Arnaud Devresse
(A)
Anabel Diaz-Mareque
(A)
Armando Coca
(A)
Gabriel de Arriba
(G)
Björn K I Meijers
(BKI)
Maarten Naesens
(M)
Dirk Kuypers
(D)
Bruno Desschans
(B)
Annelies Tonnerlier
(A)
Karl M Wissing
(KM)
Ivana Dedinska
(I)
Giuseppina Pessolano
(G)
Shafi Malik
(S)
Evangelia Dounousi
(E)
Evangelos Papachristou
(E)
Stefan P Berger
(SP)
Esther Meijer
(E)
Jan Stephan F Sanders
(JSF)
Akin Özyilmaz
(A)
Jadranka Buturović Ponikvar
(JB)
Andreja Marn Pernat
(AM)
Damjan Kovac
(D)
Miha Arnol
(M)
Femke M Molenaar
(FM)
Arjan D van Zuilen
(AD)
Sabine C A Meijvis
(SCA)
Helma Dolmans
(H)
Ekamol Tantisattamo
(E)
Pasquale Esposito
(P)
Jean-Marie Krzesinski
(JM)
Jean Damacène Barahira
(JD)
Maurizio Gallieni
(M)
Paloma Leticia Martin-Moreno
(PL)
Gabriele Guglielmetti
(G)
Gabriella Guzzo
(G)
Nestor Toapanta
(N)
Maria Jose Soler
(MJ)
Antinus J Luik
(AJ)
Willi H M van Kuijk
(WHM)
Lonneke W H Stikkelbroeck
(LWH)
Marc M H Hermans
(MMH)
Laurynas Rimsevicius
(L)
Marco Righetti
(M)
Mahmud Islam
(M)
Nicole Heitink-Ter Braak
(N)
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of the ERA.
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