Noninvasive neuromodulation in Parkinson's disease: Neuroplasticity implication and therapeutic perspectives.
Cortical excitability
Cortical plasticity
Neurostimulation
Parkinson's disease
Transcranial electrical stimulation
Transcranial magnetic stimulation
Journal
Handbook of clinical neurology
ISSN: 0072-9752
Titre abrégé: Handb Clin Neurol
Pays: Netherlands
ID NLM: 0166161
Informations de publication
Date de publication:
2022
2022
Historique:
entrez:
17
1
2022
pubmed:
18
1
2022
medline:
19
1
2022
Statut:
ppublish
Résumé
Noninvasive brain stimulation techniques can be used to study in vivo the changes of cortical activity and plasticity in subjects with Parkinson's disease (PD). Also, an increasing number of studies have suggested a potential therapeutic effect of these techniques. High-frequency repetitive transcranial magnetic stimulation (rTMS) and anodal transcranial direct current stimulation (tDCS) represent the most used stimulation paradigms to treat motor and nonmotor symptoms of PD. Both techniques can enhance cortical activity, compensating for its reduction related to subcortical dysfunction in PD. However, the use of suboptimal stimulation parameters can lead to therapeutic failure. Clinical studies are warranted to clarify in PD the additional effects of these stimulation techniques on pharmacologic and neurorehabilitation treatments.
Identifiants
pubmed: 35034733
pii: B978-0-12-819410-2.00010-2
doi: 10.1016/B978-0-12-819410-2.00010-2
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
185-198Informations de copyright
Copyright © 2022 Elsevier B.V. All rights reserved.