Pigmentary mammary Paget disease: Clinical, dermoscopical and histological challenge.
Pigmentary mammary Paget disease
mammary Paget disease
melanoma
Journal
Dermatology reports
ISSN: 2036-7392
Titre abrégé: Dermatol Reports
Pays: Italy
ID NLM: 101566470
Informations de publication
Date de publication:
17 Nov 2021
17 Nov 2021
Historique:
received:
28
04
2021
accepted:
21
05
2021
entrez:
17
1
2022
pubmed:
18
1
2022
medline:
18
1
2022
Statut:
epublish
Résumé
A very rare variant of mammary Paget disease (MPD) is the pigmented MPD, first described in 1956. It is very difficult to distinguish this variant from melanoma both clinically and dermoscopically. The diagnosis is confirmed by histopathology and immunohistochemistry. Correct diagnosis is crucial for surgical treatment, which is different for these two diseases. We report the case of a 92-year-old woman, who presented an asymptomatic pigmented lesion of the right nipple and areola. The lesion was arisen for about 6 months and was suspected for melanoma because of clinical and dersmoscopic characteristics. Incisional biopsy revealed tumor cells, that proliferate in the major mammary ducts, and tumor cells in the overlying epidermis of the nipple, thus diagnosing pigmented mammary Paget disease. The patient underwent radical mastectomy.
Identifiants
pubmed: 35035805
doi: 10.4081/dr.2021.9235
pmc: PMC8696191
doi:
Types de publication
Journal Article
Langues
eng
Pagination
9235Informations de copyright
©Copyright: the Author(s).
Déclaration de conflit d'intérêts
Conflict of interest: The authors declare no potential conflict of interest.
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