The impact of ethnicity on stroke care access and patient outcomes: a New Zealand nationwide observational study.
Disparities
Epidemiology
Ethnicity
Health services research
Indigenous
Outcome resarch
Stroke
Journal
The Lancet regional health. Western Pacific
ISSN: 2666-6065
Titre abrégé: Lancet Reg Health West Pac
Pays: England
ID NLM: 101774968
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
entrez:
17
1
2022
pubmed:
18
1
2022
medline:
18
1
2022
Statut:
epublish
Résumé
Ethnic inequities in stroke care access have been reported internationally but the impact on outcomes remains unclear. In New Zealand, data on ethnic stroke inequities and resultant effects on outcomes are generally limited and conflicting. In a prospective, nationwide, multi-centre observational study, we recruited consecutive adult patients with confirmed stroke from 28 hospitals between 1 May and 31 October 2018. Patient outcomes: favourable functional outcomes (modified Rankin Scale 0-2); quality of life (EQ-5D-3L); stroke/vascular events; and death at three, six and 12 months. Process measures: access to reperfusion therapies, stroke-units, investigations, secondary prevention, rehabilitation. Multivariate regression analyses assessed associations between ethnicity and outcomes and process measures. The cohort comprised 2,379 patients (median age 78 (IQR 66-85); 51·2% male; 76·7% European, 11·5% Māori, 4·8% Pacific peoples, 4·8% Asian). Non-Europeans were younger, had more risk factors, had reduced access to acute stroke units (aOR=0·78, 95%CI, 0·60-0·97), and were less likely to receive a swallow screen within 24 hours of arrival (aOR=0·72, 0·53-0·99) or MRI imaging (OR=0·66, 0·52-0·85). Māori were less frequently prescribed anticoagulants (OR=0·68, 0·47-0·98). Pacific peoples received greater risk factor counselling. Fewer non-Europeans had a favourable mRS score at three (aOR=0·67, 0·47-0·96), six (aOR=0·63, 0·40-0·98) and 12 months (aOR=0·56, 0·36-0·88), and more Māori had died by 12 months (aOR=1·76, 1·07-2·89). Non-Europeans, especially Māori, had poorer access to key stroke interventions and experience poorer outcomes. Further optimisation of stroke care targeting high-priority populations are needed to achieve equity. New Zealand Health Research Council (HRC17/037).
Sections du résumé
BACKGROUND
BACKGROUND
Ethnic inequities in stroke care access have been reported internationally but the impact on outcomes remains unclear. In New Zealand, data on ethnic stroke inequities and resultant effects on outcomes are generally limited and conflicting.
METHODS
METHODS
In a prospective, nationwide, multi-centre observational study, we recruited consecutive adult patients with confirmed stroke from 28 hospitals between 1 May and 31 October 2018. Patient outcomes: favourable functional outcomes (modified Rankin Scale 0-2); quality of life (EQ-5D-3L); stroke/vascular events; and death at three, six and 12 months. Process measures: access to reperfusion therapies, stroke-units, investigations, secondary prevention, rehabilitation. Multivariate regression analyses assessed associations between ethnicity and outcomes and process measures.
FINDINGS
RESULTS
The cohort comprised 2,379 patients (median age 78 (IQR 66-85); 51·2% male; 76·7% European, 11·5% Māori, 4·8% Pacific peoples, 4·8% Asian). Non-Europeans were younger, had more risk factors, had reduced access to acute stroke units (aOR=0·78, 95%CI, 0·60-0·97), and were less likely to receive a swallow screen within 24 hours of arrival (aOR=0·72, 0·53-0·99) or MRI imaging (OR=0·66, 0·52-0·85). Māori were less frequently prescribed anticoagulants (OR=0·68, 0·47-0·98). Pacific peoples received greater risk factor counselling. Fewer non-Europeans had a favourable mRS score at three (aOR=0·67, 0·47-0·96), six (aOR=0·63, 0·40-0·98) and 12 months (aOR=0·56, 0·36-0·88), and more Māori had died by 12 months (aOR=1·76, 1·07-2·89).
INTERPRETATION
CONCLUSIONS
Non-Europeans, especially Māori, had poorer access to key stroke interventions and experience poorer outcomes. Further optimisation of stroke care targeting high-priority populations are needed to achieve equity.
FUNDING
BACKGROUND
New Zealand Health Research Council (HRC17/037).
Identifiants
pubmed: 35036976
doi: 10.1016/j.lanwpc.2021.100358
pii: S2666-6065(21)00267-4
pmc: PMC8743211
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100358Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: no disclosures, except for DC, JD and JK who report grants from the Health Research Council of New Zealand during the conduct of the study; DC also reports grants from National Health and Medical Research Council, grants from Medtronic, grants from Amgen, grants from Stroke Foundation, grants from Academy of Science, grants from Heart Foundation, grants from CSIRO, grants from Victorian Agency for Health Innovation, grants from Boehringer Ingelheim, grants from Melbourne Health, grants from National Institute for Health Research UK, grants from Western Australian government, grants from South Australian government, outside the submitted work. MH reports an Appointed member of Waitemata District Health Board 2016 to 2019; no other relationships or activities that could appear to have influenced the submitted work.
Références
J Stroke Cerebrovasc Dis. 2014 Feb;23(2):327-34
pubmed: 23680690
Clin Rehabil. 2012 Jun;26(6):493-501
pubmed: 22087047
PLoS One. 2015 Aug 20;10(8):e0134609
pubmed: 26291829
N Z Med J. 2021 May 21;134(1535):7-10
pubmed: 34012135
BMC Neurol. 2011 Jun 30;11:81
pubmed: 21714938
Neuroepidemiology. 2020;54(5):427-432
pubmed: 32957111
Lancet Neurol. 2006 Feb;5(2):130-9
pubmed: 16426989
JMIR Res Protoc. 2021 Jan 12;10(1):e25374
pubmed: 33433396
Stroke. 2017 Dec;48(12):3329-3335
pubmed: 29089456
Stroke Res Treat. 2014;2014:950746
pubmed: 25028619
Interv Neurol. 2018 Oct;7(6):389-398
pubmed: 30410516
Stroke. 2011 Aug;42(8):2217-21
pubmed: 21719765
Lancet. 2006 Jun 17;367(9527):2005-9
pubmed: 16782491
Intern Med J. 2019 Aug;49(8):962-968
pubmed: 30907045
N Z Med J. 2019 Dec 13;132(1507):48-56
pubmed: 31830016
Stroke. 2006 Oct;37(10):2567-72
pubmed: 16946158
J Natl Med Assoc. 2001 Feb;93(2):43-6
pubmed: 12653381
N Z Med J. 2002 Mar 8;115(1149):98-100
pubmed: 11999231
N Z Med J. 2016 Jul 01;129(1437):8-14
pubmed: 27362594
Soc Sci Med. 2006 Sep;63(6):1428-41
pubmed: 16740349
Lancet. 2009 Jul 4;374(9683):76-85
pubmed: 19577696
Ethn Dis. 2013 Winter;23(1):29-34
pubmed: 23495619
Circulation. 2010 Apr 6;121(13):1492-501
pubmed: 20308617
Lancet Neurol. 2019 May;18(5):439-458
pubmed: 30871944