Normalized Subendocardial Myocardial Attenuation on Coronary Computed Tomography Angiography Predicts Postoperative Adverse Cardiovascular Events: Coronary CTA VISION Substudy.

Aged Computed Tomography Angiography / methods Coronary Angiography / methods Coronary Artery Disease / diagnosis Coronary Circulation / physiology Coronary Vessels / diagnostic imaging Female Humans Male Multidetector Computed Tomography Myocardial Perfusion Imaging / methods Plaque, Atherosclerotic / diagnosis Predictive Value of Tests Tomography, Emission-Computed, Single-Photon
angiography computed tomography coronary artery disease myocardial infarction perfusion

Journal

Circulation. Cardiovascular imaging
ISSN: 1942-0080
Titre abrégé: Circ Cardiovasc Imaging
Pays: United States
ID NLM: 101479935

Informations de publication

Date de publication:
01 2022
Historique:
entrez: 18 1 2022
pubmed: 19 1 2022
medline: 26 2 2022
Statut: ppublish

Résumé

Abnormalities in computed tomography myocardial perfusion has been associated with coronary artery disease and major adverse cardiovascular events (MACE). We sought to investigate if subendocardial attenuation using coronary computed tomography angiography predicts MACE 30 days postelective noncardiac surgery. Using a 17-segment model, coronary computed tomography angiography images were analyzed for subendocardial and transmural attenuation and the corresponding blood pool. The segment with the lowest subendocardial attenuation and transmural attenuation were normalized to the segment with the highest subendocardial and transmural attenuation, respectively (SUB Of a total of 995 coronary CTA VISION (Coronary Computed Tomographic Angiography and Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study) patients, 735 had available images and complete data for these analyses. Among these patients, 60 had MACE. Based on Revised Cardiovascular Risk Index, 257, 302, 138, and 38 patients had scores of 0, 1, 2, and ≥3, respectively. On coronary computed tomography angiography, 75 patients had normal coronary arteries, 297 patients had nonobstructive coronary artery disease, 264 patients had obstructive disease, and 99 patients had extensive obstructive coronary artery disease. SUB Our study demonstrates that SUB

Sections du résumé

BACKGROUND
Abnormalities in computed tomography myocardial perfusion has been associated with coronary artery disease and major adverse cardiovascular events (MACE). We sought to investigate if subendocardial attenuation using coronary computed tomography angiography predicts MACE 30 days postelective noncardiac surgery.
METHODS
Using a 17-segment model, coronary computed tomography angiography images were analyzed for subendocardial and transmural attenuation and the corresponding blood pool. The segment with the lowest subendocardial attenuation and transmural attenuation were normalized to the segment with the highest subendocardial and transmural attenuation, respectively (SUB
RESULTS
Of a total of 995 coronary CTA VISION (Coronary Computed Tomographic Angiography and Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study) patients, 735 had available images and complete data for these analyses. Among these patients, 60 had MACE. Based on Revised Cardiovascular Risk Index, 257, 302, 138, and 38 patients had scores of 0, 1, 2, and ≥3, respectively. On coronary computed tomography angiography, 75 patients had normal coronary arteries, 297 patients had nonobstructive coronary artery disease, 264 patients had obstructive disease, and 99 patients had extensive obstructive coronary artery disease. SUB
CONCLUSIONS
Our study demonstrates that SUB

Identifiants

DOI: 10.1161/CIRCIMAGING.121.012654 PMID: 35041449
pubmed: 35041449
doi: 10.1161/CIRCIMAGING.121.012654
doi:

Banques de données

ClinicalTrials.gov
['NCT01635309']

Types de publication

Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e012654

Subventions

Organisme : CIHR
Pays : Canada

Auteurs

Jeroen Walpot (J)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
ORCID: 0000-0001-9226-545X

Samia Massalha (S)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Pranisha Jayasinghe (P)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Madiha Sadaf (M)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Owen Clarkin (O)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Laura Godkin (L)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Ashwin Sharma (A)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Indeevari Ratnayake (I)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Kara Godkin (K)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
ORCID: 0000-0003-4871-0039

Kateleen Jia (K)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Alomgir Hossain (A)

Cardiovascular Research Methods Centre (A.H.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
ORCID: 0000-0002-7614-0072

Andrew M Crean (AM)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Department of Radiology, University of Ottawa, Ontario, Canada (A.M.C., B.J.W.C.).
ORCID: 0000-0002-2038-9178

Matthew Chan (M)

Department of Anesthesia and Intensive Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region (M.C.).

Craig Butler (C)

Department of Medicine (Cardiology), Alberta Heart Institute and University of Alberta, Edmonton, Alberta, Canada (C.B.).

Vikas Tandon (V)

Population Health Research Institute and Department of Medicine, David Braley Cardiac, Vascular, and Stroke Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada (V.T., P.J.D., T.S.).

Peter Nagele (P)

Department of Anesthesiology (P.N.), Washington University School of Medicine, St. Louis, MO.
Department of Anesthesia and Critical Care, University of Chicago, IL (P.N.).
ORCID: 0000-0001-8369-3858

Pamela K Woodard (PK)

Mallinckrodt Institute of Radiology (P.K.W.), Washington University School of Medicine, St. Louis, MO.

Marko Mrkobrada (M)

Department of Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada (M.M.).

Wojciech Szczeklik (W)

Department of Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland (W.S.).
ORCID: 0000-0002-1349-1123

Yang Faridah Abdul Aziz (YFA)

Department of Biomedical Imaging, University Malaya Research Imaging Centre, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia (Y.F.A.A.).
ORCID: 0000-0002-0869-1972

Bruce Biccard (B)

Department of Anaesthesia and Perioperative Medicine, Groote Schuur Hospital, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa (B.B.).

P J Devereaux (PJ)

Population Health Research Institute and Department of Medicine, David Braley Cardiac, Vascular, and Stroke Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada (V.T., P.J.D., T.S.).

Tej Sheth (T)

Population Health Research Institute and Department of Medicine, David Braley Cardiac, Vascular, and Stroke Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada (V.T., P.J.D., T.S.).

Benjamin J W Chow (BJW)

Division of Cardiology (J.W., S.M., P.J., M.S., O.C., L.G., A.S., I.R., K.G., K.J., A.M.C., B.J.W.C.), University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Department of Radiology, University of Ottawa, Ontario, Canada (A.M.C., B.J.W.C.).
ORCID: 0000-0001-8631-0234

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Tomographie à rayons X › Tomodensitométrie › Angiographie par tomodensitométrie › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Tests de la fonction cardiaque › Coronarographie › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Ischémie myocardique › Maladie coronarienne › Maladie des artères coronaires › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Circulation sanguine › Circulation coronarienne › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Veines › Vaisseaux coronaires › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Tomographie à rayons X › Tomodensitométrie › Tomodensitométrie hélicoïdale › Tomodensitométrie multidétecteurs › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Imagerie de perfusion › Imagerie de perfusion myocardique › Normalized Subendocardial Myocardial...
questionsmedicales.fr › États, signes et symptômes pathologiques › États anatomopathologiques › Plaque d'athérosclérose › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Valeur prédictive des tests › Normalized Subendocardial Myocardial...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission monophotonique › Normalized Subendocardial Myocardial...