Role of monogenic diabetes genes on beta cell function in Italian patients with newly diagnosed type 2 diabetes. The Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 13.
Insulin secretion
MODY beta-cell function
MODY genes
SNP genetics
Type 2 diabetes
Journal
Diabetes & metabolism
ISSN: 1878-1780
Titre abrégé: Diabetes Metab
Pays: France
ID NLM: 9607599
Informations de publication
Date de publication:
07 2022
07 2022
Historique:
received:
26
08
2021
revised:
27
10
2021
accepted:
25
11
2021
pubmed:
20
1
2022
medline:
3
8
2022
entrez:
19
1
2022
Statut:
ppublish
Résumé
We tested the hypothesis that common genetic variability of beta-cell genes responsible for monogenic diabetes may affect beta cell function in type 2 diabetes mellitus (T2DM). We studied 794 drug- naïve GAD-negative patients with newly diagnosed T2DM (age: median=59 years; I.Q. range: 52-66; body mass index: 29.3 kg/m
Identifiants
pubmed: 35045332
pii: S1262-3636(22)00006-4
doi: 10.1016/j.diabet.2022.101323
pii:
doi:
Substances chimiques
C-Peptide
0
Glucose
IY9XDZ35W2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101323Informations de copyright
Copyright © 2022 Elsevier Masson SAS. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.