Health trends, inequalities and opportunities in South Africa's provinces, 1990-2019: findings from the Global Burden of Disease 2019 Study.

HIV health policy healthcare disparities public health

Journal

Journal of epidemiology and community health
ISSN: 1470-2738
Titre abrégé: J Epidemiol Community Health
Pays: England
ID NLM: 7909766

Informations de publication

Date de publication:
19 Jan 2022
Historique:
received: 15 06 2021
accepted: 14 12 2021
pubmed: 21 1 2022
medline: 21 1 2022
entrez: 20 1 2022
Statut: aheadofprint

Résumé

Over the last 30 years, South Africa has experienced four 'colliding epidemics' of HIV and tuberculosis, chronic illness and mental health, injury and violence, and maternal, neonatal, and child mortality, which have had substantial effects on health and well-being. Using data from the 2019 Global Burden of Diseases, Injuries and Risk Factors Study (GBD 2019), we evaluated national and provincial health trends and progress towards important Sustainable Development Goal targets from 1990 to 2019. We analysed GBD 2019 estimates of mortality, non-fatal health loss, summary health measures and risk factor burden, comparing trends over 1990-2007 and 2007-2019. Additionally, we decomposed changes in life expectancy by cause of death and assessed healthcare system performance. Across the nine provinces, inequalities in mortality and life expectancy increased over 1990-2007, largely due to differences in HIV/AIDS, then decreased over 2007-2019. Demographic change and increases in non-communicable diseases nearly doubled the number of years lived with disability between 1990 and 2019. From 1990 to 2019, risk factor burdens generally shifted from communicable and nutritional disease risks to non-communicable disease and injury risks; unsafe sex remained the top risk factor. Despite widespread improvements in healthcare system performance, the greatest gains were generally in economically advantaged provinces. Reductions in HIV/AIDS and related conditions have led to improved health since 2007, though most provinces still lag in key areas. To achieve health targets, provincial governments should enhance health investments and exchange of knowledge, resources and best practices alongside populations that have been left behind, especially following the COVID-19 pandemic.

Sections du résumé

BACKGROUND BACKGROUND
Over the last 30 years, South Africa has experienced four 'colliding epidemics' of HIV and tuberculosis, chronic illness and mental health, injury and violence, and maternal, neonatal, and child mortality, which have had substantial effects on health and well-being. Using data from the 2019 Global Burden of Diseases, Injuries and Risk Factors Study (GBD 2019), we evaluated national and provincial health trends and progress towards important Sustainable Development Goal targets from 1990 to 2019.
METHODS METHODS
We analysed GBD 2019 estimates of mortality, non-fatal health loss, summary health measures and risk factor burden, comparing trends over 1990-2007 and 2007-2019. Additionally, we decomposed changes in life expectancy by cause of death and assessed healthcare system performance.
RESULTS RESULTS
Across the nine provinces, inequalities in mortality and life expectancy increased over 1990-2007, largely due to differences in HIV/AIDS, then decreased over 2007-2019. Demographic change and increases in non-communicable diseases nearly doubled the number of years lived with disability between 1990 and 2019. From 1990 to 2019, risk factor burdens generally shifted from communicable and nutritional disease risks to non-communicable disease and injury risks; unsafe sex remained the top risk factor. Despite widespread improvements in healthcare system performance, the greatest gains were generally in economically advantaged provinces.
CONCLUSIONS CONCLUSIONS
Reductions in HIV/AIDS and related conditions have led to improved health since 2007, though most provinces still lag in key areas. To achieve health targets, provincial governments should enhance health investments and exchange of knowledge, resources and best practices alongside populations that have been left behind, especially following the COVID-19 pandemic.

Identifiants

pubmed: 35046100
pii: jech-2021-217480
doi: 10.1136/jech-2021-217480
pmc: PMC8995905
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : FIC NIH HHS
ID : D43 TW010937
Pays : United States
Organisme : Medical Research Council
ID : MR/S005242/1
Pays : United Kingdom

Informations de copyright

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: AES reports personal fees from Servier, Novartis,Takeda, Omron Healthcare, and Abbott, outside the submitted work. DJS reports personal fees from Lundbeck, Takeda, Johnson & Johnson, and Servier, outside the submitted work.

Références

N Engl J Med. 2014 Jan 2;370(1):60-8
pubmed: 24382066
Lancet. 2009 Sep 5;374(9692):759-60
pubmed: 19709726
Lancet. 2015 Dec 5;386(10010):2257-74
pubmed: 26382241
Lancet. 2020 Oct 17;396(10258):1223-1249
pubmed: 33069327
N Engl J Med. 2014 Oct 2;371(14):1344-53
pubmed: 25265493
BMC Public Health. 2012 Jul 31;12:578
pubmed: 22849711
Lancet. 2020 Oct 17;396(10258):1160-1203
pubmed: 33069325
BMC Public Health. 2008 Aug 14;8:289
pubmed: 18702821
S Afr Med J. 2003 Sep;93(9):682-8
pubmed: 14635557
J Public Health Policy. 2011;32 Suppl 1:S102-23
pubmed: 21730985
Lancet. 2018 Jun 2;391(10136):2236-2271
pubmed: 29893224
Front Public Health. 2020 Oct 19;8:504
pubmed: 33194933
Lancet. 2009 Sep 5;374(9692):817-34
pubmed: 19709728
Lancet. 2018 Sep 1;392(10149):735-736
pubmed: 30191827
Paediatr Respir Rev. 2020 Sep;35:70-74
pubmed: 32654854
Lancet. 2009 Sep 19;374(9694):1011-1022
pubmed: 19709732
Lancet Glob Health. 2020 Oct;8(10):e1264-e1272
pubmed: 32687792
Lancet Glob Health. 2016 Sep;4(9):e642-53
pubmed: 27539806
Am J Public Health. 2011 Jan;101(1):165-72
pubmed: 21148716
J Int AIDS Soc. 2015 Dec 02;18(Suppl 6):20745
pubmed: 26639121
PLoS Med. 2008 Jul 15;5(7):e152
pubmed: 18630984
BMC Public Health. 2020 Dec 14;20(1):1908
pubmed: 33317507
Front Public Health. 2015 Nov 16;3:253
pubmed: 26636055
S Afr Med J. 2020 Feb 26;110(3):188-191
pubmed: 32657694
Lancet Respir Med. 2020 Jan;8(1):19
pubmed: 31706931
Lancet. 2009 Sep 19;374(9694):1023-1031
pubmed: 19709737
Lancet. 2012 Dec 8;380(9858):2029-43
pubmed: 23201214
BMJ. 2019 Jan 28;364:l295
pubmed: 30692081
Lancet. 2020 Oct 17;396(10258):1204-1222
pubmed: 33069326
PLoS Med. 2017 Dec 12;14(12):e1002468
pubmed: 29232366
PLoS Biol. 2016 Mar 02;14(3):e1002372
pubmed: 26933962

Auteurs

Tom Achoki (T)

Research, Africa Institute for Health Policy, Nairobi, Kenya.
Center for Pharmaceutical Policy and Regulation, Utrecht University, Utrecht, Netherlands.

Benn Sartorius (B)

Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, Washington, USA.

David Watkins (D)

Department of Medicine, University of Washington, Seattle, WA, USA.
Department of Medicine, University of Cape Town, Cape Town, South Africa.

Scott D Glenn (SD)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Andre Pascal Kengne (AP)

Department of Medicine, University of Cape Town, Cape Town, South Africa.
Non-communicable Diseases Research Unit, Medical Research Council South Africa, Cape Town, South Africa.

Tolu Oni (T)

MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
School of Public Health and Family Medicine, University of Cape Town, Rondebosch, Western Cape, South Africa.

Charles Shey Wiysonge (CS)

School of Public Health and Family Medicine, University of Cape Town, Rondebosch, Western Cape, South Africa.
Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa.

Alexandra Walker (A)

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Olatunji O Adetokunboh (OO)

Centre of Excellence for Epidemiological Modelling and Analysis, Stellenbosch University, Stellenbosch, South Africa.
Department of Global Health, Stellenbosch University, Stellenbosch, South Africa.

Tesleem Kayode Babalola (TK)

Discipline of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa.
Department of Community Health and Primary Care, University of Lagos, Lagos, Nigeria.

Obasanjo Afolabi Bolarinwa (OA)

Discipline of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa.

Mareli M Claassens (MM)

Department of Biochemistry and Microbiology, University of Namibia, Windhoek, Namibia.
Department of Paediatrics and Child Health, Stellenbosch University, Tygerberg, South Africa.

Richard G Cowden (RG)

Department of Psychology, University of the Free State, Park WEst, Free State, South Africa.

Candy T Day (CT)

Health Systems Research Unit, Health System Trust, Westville, South Africa.

Oluchi Ezekannagha (O)

Independent Consultant, Awka, Nigeria.
International Institute of Tropical Agriculture, Ibadan, Nigeria.

Themba G Ginindza (TG)

Discipline of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa.

Chidozie C D Iwu (CCD)

School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.

Chinwe Juliana Iwu (CJ)

Department of Global Health, Stellenbosch University, Stellenbosch, South Africa.
South African Medical Research Council, Cape Town, South Africa.

Innocent Karangwa (I)

Department of Statistics and Population Studies, University of the Western Cape, Cape Town, South Africa.

Patrick Dmc Katoto (PD)

Department of Global Health, Stellenbosch University, Stellenbosch, South Africa.
Centre for Tropical Diseases and Global Health, Catholic University of Bukavu, Bukavu, Democratic Republic of Congo.

Nuworza Kugbey (N)

University of Environment and Sustainable Development, Somanya, Ghana.

Desmond Kuupiel (D)

School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
Department of Nursing, Research for Sustainable Development Consult, Sunyani, Ghana.

Phetole Walter Mahasha (PW)

Grants, Innovation and Product Development Unit, South African Medical Research Council, Cape Town, South Africa.

Tivani Phosa Mashamba-Thompson (TP)

Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

George A Mensah (GA)

Department of Medicine, University of Cape Town, Cape Town, South Africa.
Center for Translation Research and Implementation Science, National Institutes of Health, Bethesda, Maryland, USA.

Duduzile Edith Ndwandwe (DE)

Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa.

Chukwudi A Nnaji (CA)

School of Public Health and Family Medicine, University of Cape Town, Rondebosch, Western Cape, South Africa.
South African Medical Research Council, Cape Town, South Africa.

Mpiko Ntsekhe (M)

Division of Cardiology, University of Cape Town, Rondebosch, Western Cape, South Africa.
The Cardiac Clinic, Groote Schuur Hospital, Cape Town, South Africa.

Thomas Elliot Nyirenda (TE)

Department of Global Health, Stellenbosch University, Stellenbosch, South Africa.
European and Developing Countries Clinical Trials Partnership (EDCTP), European Commission, Cape Town, South Africa.

Julius Nyerere Odhiambo (JN)

Discipline of Public Health Medicine, University of KwaZulu-Natal, Durban, South Africa.
Department of Management Science and Technology, Technical University of Kenya, Nairobi, Nairobi, Kenya.

Kwaku Oppong Asante (K)

Department of Psychology, University of Ghana, Accra, Ghana.

Charles D H Parry (CDH)

Alcohol, Tobacco & Other Drug Research Unit, South African Medical Research Council, Cape Town, South Africa.
Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.

Julian David Pillay (JD)

Department of Basic Medical Sciences, Durban University of Technology, Durban, South Africa.

Aletta Elisabeth Schutte (AE)

School of Public Health and Community Medicine, University of New South Wales, Sydney, New South Wales, Australia.
The George Institute for Global Health, Sydney, New South Wales, Australia.

Soraya Seedat (S)

Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa.

Karen Sliwa (K)

Hatter Institute Department of Medicine, University of Cape Town, Cape Town, South Africa.

Dan J Stein (DJ)

Unit on Risk and Resilience in Mental Disorders, South African Medical Research Council, Cape Town, South Africa.

Frank C Tanser (FC)

University of KwaZulu-Natal, Durban, South Africa.
Africa Health Research Institute, Berea, South Africa.

Ushotanefe Useh (U)

Health Sciences Department, North-West University, Mmbatho, South Africa.

Heather J Zar (HJ)

Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.
Unit on Child & Adolescent Health, Medical Research Council South Africa, Cape Town, South Africa.

Liesl J Zühlke (LJ)

Department of Medicine, University of Cape Town, Cape Town, South Africa.
Department of Paediatrics and Child Health, University of Cape Town, Cape Town, South Africa.

Bongani M Mayosi (BM)

University of Cape Town, Cape Town, South Africa.

Simon I Hay (SI)

Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, Washington, USA.
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Christopher J L Murray (CJL)

Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, Washington, USA.
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Mohsen Naghavi (M)

Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, Washington, USA nagham@uw.edu.
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Classifications MeSH