Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis.

HFE gene age of onset colon cancer ferritin genetic iron population screening

Journal

HGG advances
ISSN: 2666-2477
Titre abrégé: HGG Adv
Pays: United States
ID NLM: 101772885

Informations de publication

Date de publication:
22 Oct 2020
Historique:
received: 30 07 2020
accepted: 12 08 2020
entrez: 20 1 2022
pubmed: 25 8 2020
medline: 25 8 2020
Statut: epublish

Résumé

Homozygotes for the higher penetrance hemochromatosis risk allele,

Identifiants

pubmed: 35047832
doi: 10.1016/j.xhgg.2020.100010
pii: S2666-2477(20)30010-5
pmc: PMC8756515
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100010

Subventions

Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA182883
Pays : United States

Informations de copyright

© 2020 The Authors.

Déclaration de conflit d'intérêts

D.R.C. is a paid consultant for UnitedHealth Group Research and Development. H.H. is on the Scientific Advisory Boards of Invitae Genetics, Genome Medical, and Promega. She is a consultant for 23and Me. She conducts collaborative research with Invitae Genetics, Myriad Genetic Laboratories, and Ambry Genetics. She holds stocks in Genome Medical. J.M., P.F., E.K., and members of the 23andMe Research Team are current or former employees of 23andMe and hold stock or stock options in 23andMe. S.B.G. is a founder of Brogent International with equity.

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Auteurs

Gail P Jarvik (GP)

University of Washington Medical Center, Seattle, WA, USA.

Xiaoliang Wang (X)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Pierre Fontanillas (P)

23andMe, Sunnyvale, CA, USA.

Esther Kim (E)

23andMe, Sunnyvale, CA, USA.

Sirisak Chanprasert (S)

University of Washington Medical Center, Seattle, WA, USA.

Adam S Gordon (AS)

Northwestern University, Evanston, IL, USA.

Lisa Bastarache (L)

Vanderbilt Medical Center, Atlanta, GA, USA.

Kris V Kowdley (KV)

Liver Institute Northwest, Seattle, WA, USA.

Tabitha Harrison (T)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Elisabeth A Rosenthal (EA)

University of Washington Medical Center, Seattle, WA, USA.

Ian B Stanaway (IB)

University of Washington Medical Center, Seattle, WA, USA.

Stéphane Bézieau (S)

Centre Hospitalier Universitaire (CHU) Nantes, France.

Stephanie J Weinstein (SJ)

National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Polly A Newcomb (PA)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
School of Public Health, University of Washington, Seattle, WA.

Graham Casey (G)

University of Virginia, Charlottesville, VA, USA.

Elizabeth A Platz (EA)

Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Kala Visvanathan (K)

Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Loic Le Marchand (L)

University of Hawaii Cancer Center, Honolulu, HI, USA.

Cornelia M Ulrich (CM)

University of Utah, Salt Lake City, UT, USA.

Sheetal Hardikar (S)

University of Utah, Salt Lake City, UT, USA.

Christopher I Li (CI)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Franzel J B van Duijnhoven (FJB)

Division of Human Nutrition and Health, Wageningen University and Research Wageningen, the Netherlands.

Andrea Gsur (A)

Medical University Vienna, Vienna, Austria.

Peter T Campbell (PT)

American Cancer Society, Atlanta, GA, USA.

Victor Moreno (V)

Oncology Data Analytics Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP) and Department of Clinical Sciences, Faculty of Medicine, University of Barcelona (UB), L'Hospitalet, 08908, Barcelona, Spain.

Pavel Vodička (P)

Institute of Experimental Medicine, Czech Academy of Sciences, Biomedical Center, Medical Faculty Pilsen and 1st Medical Faculty, Charles University, Prague, Czech Republic.

Hermann Brenner (H)

German Cancer Research Center (DKFZ), Heidelberg, Germany.

Jenny Chang-Claude (J)

German Cancer Research Center (DKFZ), Heidelberg, Germany.

Michael Hoffmeister (M)

German Cancer Research Center (DKFZ), Heidelberg, Germany.

Martha L Slattery (ML)

University of Utah, Salt Lake City, UT, USA.

Marc J Gunter (MJ)

Nutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France.

Elom K Aglago (EK)

Nutrition and Metabolism Section, International Agency for Research on Cancer (IARC-WHO), Lyon, France.

Sergi Castellví-Bel (S)

Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.

Sun-Seog Kweon (SS)

Chonnam National University Medical School, Gwangju, Korea.

Andrew T Chan (AT)

Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Li Li (L)

University of Virginia, Charlottesville, VA, USA.

Wei Zheng (W)

Division of Epidemiology, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA.

D Timothy Bishop (DT)

University of Leeds, Leeds, UK.

Graham G Giles (GG)

Cancer Council Victoria, Melbourne, VIC, Australia.
University of Melbourne, Melbourne, VIC, Australia.
Monash University, Melbourne, VIC, Australia.

Gad Rennert (G)

Lady Davis Carmel Medical Center, Haifa, Israel.

Kenneth Offit (K)

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Temitope O Keku (TO)

University of North Carolina, Chapel Hill, NC, USA.

Michael O Woods (MO)

Memorial University of Newfoundland, St. John's, NL, Canada.

Jochen Hampe (J)

Technische Universität Dresden (TU Dresden), Dresden, Germany.

Bethan Van Guelpen (B)

Department of Radiation Sciences, Oncology, Umeå University and Wallenberg Centre for Molecular Medicine, Umeå University, Sweden.

Steven J Gallinger (SJ)

University of Toronto, Toronto, ON, Canada.

Albert de la Chapelle (A)

The Ohio State University, Columbus, OH, USA.

Heather Hampel (H)

The Ohio State University, Columbus, OH, USA.

Sonja I Berndt (SI)

National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Catherine M Tangen (CM)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Annika Lindblom (A)

Karolinska University Hospital, Stockholm, Sweden.

Alicja Wolk (A)

Karolinska Institutet, Stockholm, Sweden.
Uppsala University, Uppsala, Sweden.

Andrea Burnett-Hartman (A)

Kaiser Permanente Colorado, Denver, CO, USA.

Anna H Wu (AH)

University of Southern California, Los Angeles, CA, USA.

Emily White (E)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Stephen B Gruber (SB)

City of Hope Comprehensive Cancer Center, Duarte, CA, USA.

Mark A Jenkins (MA)

Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, VIC, Australia.

Joanna Mountain (J)

23andMe, Sunnyvale, CA, USA.

Ulrike Peters (U)

Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Department of Epidemiology, University of Washington School of Medicine, Seattle, WA, USA.

David R Crosslin (DR)

University of Washington Medical Center, Seattle, WA, USA.

Classifications MeSH