Discovery of a neuromuscular syndrome caused by biallelic variants in

ASCC3 Activating Signal Cointegrator 1 Complex Subunit 3 neurogenetics neuromuscular

Journal

HGG advances
ISSN: 2666-2477
Titre abrégé: HGG Adv
Pays: United States
ID NLM: 101772885

Informations de publication

Date de publication:
08 Apr 2021
Historique:
received: 14 09 2020
accepted: 13 01 2021
entrez: 20 1 2022
pubmed: 21 1 2022
medline: 21 1 2022
Statut: epublish

Résumé

Activating Signal Cointegrator 1 Complex, Subunit 3 (ASCC3) is part of the four-part ASC-1 transcriptional cointegrator complex. This complex includes ASCC1 (associated with spinal muscular atrophy with congenital bone fractures 2), TRIP4 (associated with spinal muscular atrophy with congenital bone fractures 1), and ASCC2 (not yet associated with human disease.)

Identifiants

pubmed: 35047834
doi: 10.1016/j.xhgg.2021.100024
pii: S2666-2477(21)00005-1
pmc: PMC8756546
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100024

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© 2021 The Author(s).

Déclaration de conflit d'intérêts

The authors declare no competing interests.

Références

Nucleic Acids Res. 2018 Dec 14;46(22):11939-11951
pubmed: 30398641
Cell. 2017 Feb 23;168(5):843-855.e13
pubmed: 28215706
J Biol Chem. 2018 Aug 31;293(35):13524-13533
pubmed: 29997253
Hum Mutat. 2015 Oct;36(10):928-30
pubmed: 26220891
Hum Mol Genet. 2016 Apr 15;25(8):1559-73
pubmed: 27008887
Nature. 2011 Sep 21;478(7367):57-63
pubmed: 21937992
Am J Hum Genet. 2016 Mar 3;98(3):473-489
pubmed: 26924529
J Med Genet. 1991 May;28(5):345-8
pubmed: 1865475

Auteurs

Divya Nair (D)

Children's Hospital of Philadelphia, Philadephia, PA, USA.

Dong Li (D)

Children's Hospital of Philadelphia, Philadephia, PA, USA.

Hannah Erdogan (H)

Children's Hospital of Philadelphia, Philadephia, PA, USA.

Andrew Yoon (A)

Children's Hospital of Philadelphia, Philadephia, PA, USA.

Margaret H Harr (MH)

Children's Hospital of Philadelphia, Philadephia, PA, USA.

Gaber Bergant (G)

Clinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Borut Peterlin (B)

Clinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Maruša Škrjanec Pušenjak (M)

Clinical Institute of Genomic Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Parul Jayakar (P)

Nicklaus Children's Hospital, Miami, FL, USA.

Rolph Pfundt (R)

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboudumc, the Netherlands.

Sandra Jansen (S)

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboudumc, the Netherlands.

Kirsty McWalter (K)

GeneDx, Gaithersburg, MD, USA.

Alpa Sidhu (A)

University of Iowa, Iowa City, IA, USA.

Sheila Saliganan (S)

Ambry Genetics, Aliso Viejo, CA, USA.

Emanuele Agolini (E)

Translational Cytogenomics Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Arthur Jacob (A)

Department of Genetic Medicine, Genetic Intelligence Laboratory, Weill Cornell Medicine in Qatar, Education City, Al Luqta St, Ar-Rayyan, Qatar.

Jennifer Pasquier (J)

Department of Genetic Medicine, Genetic Intelligence Laboratory, Weill Cornell Medicine in Qatar, Education City, Al Luqta St, Ar-Rayyan, Qatar.

Rafii Arash (R)

Department of Genetic Medicine, Genetic Intelligence Laboratory, Weill Cornell Medicine in Qatar, Education City, Al Luqta St, Ar-Rayyan, Qatar.

Kimia Kahrizi (K)

Genetics Research Center University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Hossein Najmabadi (H)

Genetics Research Center University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Hans-Hilger Ropers (HH)

Max Planck Institute for Molecular GeneticsIhnestr. 63-73, Berlin, Germany.

Elizabeth J Bhoj (EJ)

Children's Hospital of Philadelphia, Philadephia, PA, USA.

Classifications MeSH