Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review.
cognition
cognitive rehabilitation
memory
multiple sclerosis
review
Journal
Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646
Informations de publication
Date de publication:
30 Dec 2021
30 Dec 2021
Historique:
received:
08
12
2021
revised:
27
12
2021
accepted:
27
12
2021
entrez:
21
1
2022
pubmed:
22
1
2022
medline:
22
1
2022
Statut:
epublish
Résumé
In recent years, several blinded randomized controlled trials (RCT) have been conducted on cognitive rehabilitation (CR) in adults with multiple sclerosis (MS). To review all blinded RCTs on CR in MS published since 2013. The National Library of Medicine database (Medline) and PSYCINFO were searched using the keywords MS and CR or cognitive training or NP rehabilitation or memory rehabilitation or attention rehabilitation. After the exclusion of some papers not specifically focused on CR, a final list of 26 studies was established. The papers belong to three main categories: individual specific rehabilitation (8studies), group rehabilitation (4 studies), and computerized training (CT) (14 studies), while one study combined group rehabilitation and CT. Among the individual rehabilitation studies, 5 were devoted to memory, and most of the 19 other selected studies were about several cognitive domains. Most of the studies mainly concerned RRMS patients, except for 2 studies that were carried out exclusively in progressive forms. Despite the methodological limitations of some studies and the great heterogeneity of the protocols, the results are generally in favor of the efficacy of CR in neuropsychological tests. Recent blinded RCTs about CR in MS show promising results.
Sections du résumé
BACKGROUND
BACKGROUND
In recent years, several blinded randomized controlled trials (RCT) have been conducted on cognitive rehabilitation (CR) in adults with multiple sclerosis (MS).
OBJECTIVE
OBJECTIVE
To review all blinded RCTs on CR in MS published since 2013.
METHODS
METHODS
The National Library of Medicine database (Medline) and PSYCINFO were searched using the keywords MS and CR or cognitive training or NP rehabilitation or memory rehabilitation or attention rehabilitation.
RESULTS
RESULTS
After the exclusion of some papers not specifically focused on CR, a final list of 26 studies was established. The papers belong to three main categories: individual specific rehabilitation (8studies), group rehabilitation (4 studies), and computerized training (CT) (14 studies), while one study combined group rehabilitation and CT. Among the individual rehabilitation studies, 5 were devoted to memory, and most of the 19 other selected studies were about several cognitive domains. Most of the studies mainly concerned RRMS patients, except for 2 studies that were carried out exclusively in progressive forms. Despite the methodological limitations of some studies and the great heterogeneity of the protocols, the results are generally in favor of the efficacy of CR in neuropsychological tests.
CONCLUSION
CONCLUSIONS
Recent blinded RCTs about CR in MS show promising results.
Identifiants
pubmed: 35053798
pii: brainsci12010055
doi: 10.3390/brainsci12010055
pmc: PMC8773488
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Mult Scler. 2013 Oct;19(12):1665-72
pubmed: 23459569
Acta Neurol Scand. 2018 Jun;137(6):589-597
pubmed: 29411360
Mult Scler. 2018 Nov;24(13):1665-1680
pubmed: 30303036
Mult Scler. 2017 Apr;23(5):721-733
pubmed: 28206827
Mult Scler. 2004 Dec;10(6):675-8
pubmed: 15584493
Mult Scler. 2014 Jan;20(1):91-8
pubmed: 23959713
Disabil Health J. 2018 Jul;11(3):427-434
pubmed: 29477372
Neurology. 1991 May;41(5):685-91
pubmed: 2027484
J Integr Neurosci. 2020 Jun 30;19(2):341-347
pubmed: 32706198
Front Neurol. 2019 Mar 20;10:261
pubmed: 30949122
Neural Plast. 2016;2016:4292585
pubmed: 28116167
J Neurol Sci. 2013 Nov 15;334(1-2):154-60
pubmed: 24011606
J Clin Exp Neuropsychol. 2015;37(2):113-27
pubmed: 25686052
Mult Scler. 2020 Mar;26(3):354-362
pubmed: 30741103
Mult Scler. 2005 Feb;11(1):58-68
pubmed: 15732268
Mult Scler. 2019 Dec;25(14):1848-1869
pubmed: 31637963
Neurorehabil Neural Repair. 2013 May;27(4):284-95
pubmed: 23192417
Neuropsychol Rehabil. 2021 Mar;31(2):231-254
pubmed: 31752604
J Neuroeng Rehabil. 2016 Oct 4;13(1):88
pubmed: 27716336
J Int Neuropsychol Soc. 2006 Jul;12(4):549-58
pubmed: 16981607
J Neurol. 2013 Mar;260(3):776-84
pubmed: 23081755
Clin Rehabil. 2020 Feb;34(2):229-241
pubmed: 31769299
J Clin Exp Neuropsychol. 2018 May;40(4):405-410
pubmed: 28737452
PLoS One. 2017 May 11;12(5):e0177177
pubmed: 28493924
Mult Scler. 2017 Dec;23(14):1929-1937
pubmed: 28080262
Mult Scler. 2014 Jan;20(1):99-107
pubmed: 23804555
NeuroRehabilitation. 2019;45(3):349-358
pubmed: 31796695
Cochrane Database Syst Rev. 2014 Feb 11;(2):CD009131
pubmed: 24515630
J Neurol. 2013 Jun;260(6):1452-68
pubmed: 23180174
Mult Scler Relat Disord. 2021 Apr;49:102770
pubmed: 33497850
Neurology. 2013 Dec 10;81(24):2066-72
pubmed: 24212393
Front Neurol. 2018 Aug 27;9:685
pubmed: 30210426
Mult Scler. 2012 Jun;18(6):891-8
pubmed: 22190573
Mult Scler. 2015 Sep;21(10):1332-43
pubmed: 25716880
Behav Neurol. 2017;2017:5919841
pubmed: 29463950
Mult Scler. 2018 Jul;24(8):1096-1104
pubmed: 28485659
Eur Neurol. 2017;78(1-2):111-117
pubmed: 28738376
J Neurol Sci. 2020 Aug 15;415:116929
pubmed: 32460145
Neurology. 2020 Jun 2;94(22):e2373-e2383
pubmed: 32430312
Mult Scler Relat Disord. 2020 Jan 7;39:101932
pubmed: 31927200
Clin Rehabil. 2020 Jun;34(6):754-763
pubmed: 32475261
Neurorehabil Neural Repair. 2015 Jun;29(5):453-61
pubmed: 25398725