Clues for Improving the Pathophysiology Knowledge for Endometriosis Using Serum Micro-RNA Expression.
endometriosis
miRNA
pathophysiology
pathways
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
12 Jan 2022
12 Jan 2022
Historique:
received:
03
12
2021
revised:
06
01
2022
accepted:
09
01
2022
entrez:
21
1
2022
pubmed:
22
1
2022
medline:
22
1
2022
Statut:
epublish
Résumé
The pathophysiology of endometriosis remains poorly understood. The aim of the present study was to investigate functions and pathways associated with the various miRNAs differentially expressed in patients with endometriosis. Plasma samples of the 200 patients from the prospective "ENDO-miRNA" study were analyzed and all known human miRNAs were sequenced. For each miRNA, sensitivity, specificity, and ROC AUC values were calculated for the diagnosis of endometriosis. miRNAs with an AUC ≥ 0.6 were selected for further analysis. A comprehensive review of recent articles from the PubMed, Clinical Trials.gov, Cochrane Library, and Web of Science databases was performed to identify functions and pathways associated with the selected miRNAs. In total, 2633 miRNAs were found in the patients with endometriosis. Among the 57 miRNAs with an AUC ≥ 0.6: 20 had never been reported before; one (miR-124-3p) had previously been observed in endometriosis; and the remaining 36 had been reported in benign and malignant disorders. miR-124-3p is involved in ectopic endometrial cell proliferation and invasion and plays a role in the following pathways: mTOR, STAT3, PI3K/Akt, NF-κB, ERK, PLGF-ROS, FGF2-FGFR, MAPK, GSK3B/
Identifiants
pubmed: 35054341
pii: diagnostics12010175
doi: 10.3390/diagnostics12010175
pmc: PMC8774370
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Conseil Régional d'Île-de-France
ID : EX024087
Organisme : Ziwig
Références
Dis Markers. 2020 Jan 23;2020:2456340
pubmed: 32076458
J Gynecol Obstet Hum Reprod. 2021 Apr;50(4):102092
pubmed: 33601073
BMC Cancer. 2021 Jul 23;21(1):849
pubmed: 34301211
J Cancer. 2021 Apr 17;12(11):3393-3406
pubmed: 33976749
Int J Mol Sci. 2018 Nov 20;19(11):
pubmed: 30463366
Exp Mol Pathol. 2021 Feb;118:104588
pubmed: 33278425
Cancer Cell Int. 2021 Aug 14;21(1):428
pubmed: 34391435
Appl Plant Sci. 2021 Apr 07;9(3):e11414
pubmed: 33854848
Acta Obstet Gynecol Scand. 2002 Mar;81(3):195-203
pubmed: 11966474
Mod Pathol. 2016 Apr;29(4):391-401
pubmed: 26847173
J Cell Physiol. 2020 Feb;235(2):629-637
pubmed: 31313842
Reprod Sci. 2021 Apr 6;:
pubmed: 33825167
Sci Signal. 2016 Nov 15;9(454):c22
pubmed: 27902446
Obstet Gynecol. 2007 Jun;109(6):1421-3
pubmed: 17540816
Biol Reprod. 2014 Sep;91(3):63
pubmed: 25100707
Bone Rep. 2020 Apr 23;12:100270
pubmed: 32395570
Oncogene. 2019 Oct;38(42):6850-6866
pubmed: 31406252
Hum Reprod. 2013 Mar;28(3):750-61
pubmed: 23293219
Cancer Cell Int. 2020 May 24;20:181
pubmed: 32489317
J Clin Med. 2019 Feb 24;8(2):
pubmed: 30813466
Genome Biol. 2009;10(3):R25
pubmed: 19261174
Reprod Biomed Online. 2015 May;30(5):553-6
pubmed: 25754227
Semin Reprod Med. 2012 Jan;30(1):39-45
pubmed: 22271293
Curr Med Sci. 2018 Jun;38(3):499-504
pubmed: 30074218
Nat Rev Drug Discov. 2020 Jul;19(7):480-494
pubmed: 32555376
Circ Res. 2017 Sep 1;121(6):628-635
pubmed: 28698179
Arch Gynecol Obstet. 2012 Sep;286(3):667-70
pubmed: 22562384
Breast Cancer Res Treat. 2013 Apr;138(3):753-60
pubmed: 23549953
Fertil Steril. 2017 Feb;107(2):e11-e12
pubmed: 27887713
Int J Mol Sci. 2017 Jul 12;18(7):
pubmed: 28704935
Pharmazie. 2016 Aug 1;71(8):434-438
pubmed: 29442029
Clin Transl Med. 2020 Oct;10(6):e197
pubmed: 33135344
Anticancer Drugs. 2022 Jan 1;33(1):e573-e583
pubmed: 34387599
Int J Mol Sci. 2018 Feb 17;19(2):
pubmed: 29463003
Cell Cycle. 2021 May 4;:1-13
pubmed: 33945401
Nat Commun. 2017 Jan 04;8:14058
pubmed: 28051067
Genome Biol. 2014;15(12):550
pubmed: 25516281
Front Oncol. 2020 Aug 04;10:1370
pubmed: 32850438
Microrna. 2015;4(1):50-6
pubmed: 25809640
J Clin Med. 2020 Apr 23;9(4):
pubmed: 32340338
Hum Reprod Update. 2012 Nov-Dec;18(6):682-702
pubmed: 22718320
Biomed Res Int. 2020 Dec 9;2020:5976127
pubmed: 33490245
Cancer Cell Int. 2020 May 16;20:171
pubmed: 32467667
BMC Cancer. 2021 May 19;21(1):575
pubmed: 34011306
Surg Oncol. 2020 Sep;34:113-120
pubmed: 32891315
Fertil Steril. 2015 May;103(5):1252-60.e1
pubmed: 25772772
Cancer Res. 2020 Apr 15;80(8):1720-1734
pubmed: 32015093
Arterioscler Thromb Vasc Biol. 2017 May;37(5):786-793
pubmed: 28336556
Hum Reprod. 2019 Sep 29;34(9):1650-1660
pubmed: 31411334
Endocrinology. 2006 Mar;147(3):1097-121
pubmed: 16306079
Fertil Steril. 1997 May;67(5):817-21
pubmed: 9130884
Eur Rev Med Pharmacol Sci. 2020 Mar;24(6):3105-3112
pubmed: 32271428
J Reprod Immunol. 2008 Oct;79(1):111-7
pubmed: 18814918
J Cancer Res Clin Oncol. 2015 Mar;141(3):431-41
pubmed: 25245053
Histol Histopathol. 2017 Sep;32(9):941-950
pubmed: 28000202
Stat Med. 1996 Feb 28;15(4):361-87
pubmed: 8668867
Fertil Steril. 2017 Dec;108(6):886-894
pubmed: 29202963
Cell Biol Toxicol. 2021 May 4;:
pubmed: 33945031
Fertil Steril. 2007 May;87(5):1231-4
pubmed: 17292364
Nucleic Acids Res. 2008 Jan;36(Database issue):D154-8
pubmed: 17991681
Diagnostics (Basel). 2020 Feb 29;10(3):
pubmed: 32121424
BMC Res Notes. 2014 Apr 04;7:212
pubmed: 24708854
Expert Rev Clin Immunol. 2011 Sep;7(5):611-26
pubmed: 21895474
Clin Rheumatol. 2021 Jun;40(6):2211-2219
pubmed: 33389220
Cell Prolif. 2020 May;53(5):e12797
pubmed: 32297697
Mol Cell Biol. 1996 May;16(5):2128-34
pubmed: 8628279
Technol Cancer Res Treat. 2021 Jan-Dec;20:15330338211019376
pubmed: 34032148
Hepatol Res. 2016 Jul;46(8):804-15
pubmed: 26583881
Sci Total Environ. 2020 Dec 1;746:141181
pubmed: 32768781
Reprod Sci. 2017 Aug;24(8):1195-1202
pubmed: 27920341
Biochem Biophys Res Commun. 2018 Jan 1;495(1):312-318
pubmed: 29117536
Einstein (Sao Paulo). 2021 Apr 26;19:eRW5704
pubmed: 33909757
Methods Mol Biol. 2017;1580:21-44
pubmed: 28439824
Lab Invest. 2017 May;97(5):530-542
pubmed: 28218742
Molecules. 2021 Feb 26;26(5):
pubmed: 33652854
Stem Cell Res Ther. 2020 Dec 1;11(1):520
pubmed: 33261656
J Neurol. 2021 Nov;268(11):4349-4361
pubmed: 34028616
Cells. 2018 Nov 06;7(11):
pubmed: 30404220
Cell Microbiol. 2018 Sep;20(9):e12859
pubmed: 29749704
Nucleic Acids Res. 2008 Dec;36(21):e141
pubmed: 18927111
Hum Reprod. 2015 Mar;30(3):632-41
pubmed: 25516558
Arch Gynecol Obstet. 2015 Sep;292(3):523-9
pubmed: 25749349
Hum Reprod Update. 2007 Jul-Aug;13(4):331-42
pubmed: 17347159
Fertil Steril. 2016 Aug;106(2):402-9
pubmed: 27179784
Hum Reprod Update. 2017 Sep 1;23(5):548-559
pubmed: 28903471
Environ Pollut. 2020 May;260:114066
pubmed: 32041029
Cell. 2009 Jan 23;136(2):215-33
pubmed: 19167326
Onco Targets Ther. 2020 Nov 04;13:11289-11299
pubmed: 33177837
Cell. 2012 Jun 8;149(6):1192-205
pubmed: 22682243
Int J Gynecol Cancer. 2006 Sep-Oct;16(5):1911-7
pubmed: 17009991
Cancer Cell. 2016 Jun 13;29(6):783-803
pubmed: 27300434
Reprod Sci. 2018 Jul;25(7):978-979
pubmed: 28100109
Lasers Med Sci. 2020 Jun;35(4):833-839
pubmed: 31485783
Immunol Invest. 2008;37(1):43-61
pubmed: 18214799
J Exp Clin Cancer Res. 2019 Oct 17;38(1):418
pubmed: 31623640
Mol Hum Reprod. 2002 Dec;8(12):1103-10
pubmed: 12468643
Gynecol Endocrinol. 2020 May;36(5):441-444
pubmed: 31663401
Aging (Albany NY). 2021 Apr 26;13(9):12607-12630
pubmed: 33901012
J Cardiovasc Pharmacol. 2020 Aug;76(2):151-158
pubmed: 32453072
Sci Signal. 2016 Nov 15;9(454):ra110
pubmed: 27902447
Stat Med. 2000 Apr 30;19(8):1059-79
pubmed: 10790680
Am J Reprod Immunol. 1995 Dec;34(6):381-5
pubmed: 8607944
J Cell Mol Med. 2020 Aug;24(16):9231-9243
pubmed: 32596993
PLoS One. 2018 Dec 17;13(12):e0209342
pubmed: 30557328
Nature. 2017 May 11;545(7653):234-237
pubmed: 28467818
Exp Mol Med. 2019 Nov 22;51(11):1-20
pubmed: 31757938
Cancers (Basel). 2020 Jul 03;12(7):
pubmed: 32635415
J Cell Biochem. 2019 Jun;120(6):9487-9494
pubmed: 30556306
Cancer Manag Res. 2020 Nov 24;12:12087-12098
pubmed: 33262657
Ann Transl Med. 2015 Jul;3(11):153
pubmed: 26244140
Hum Reprod Update. 2018 Jul 1;24(4):497-515
pubmed: 29697794
J Clin Endocrinol Metab. 2013 Jan;98(1):281-9
pubmed: 23118427
Int J Mol Sci. 2020 Jan 30;21(3):
pubmed: 32019170
J Neuropathol Exp Neurol. 2021 Feb 22;80(3):254-264
pubmed: 33225366
Am J Obstet Gynecol. 2020 Oct;223(4):557.e1-557.e11
pubmed: 32165186
Radiology. 2004 Aug;232(2):379-89
pubmed: 15205479
J Int Med Res. 2013 Dec;41(6):1803-10
pubmed: 24265332
Oncotarget. 2017 Apr 25;8(17):28939-28958
pubmed: 28423652
Int J Biol Macromol. 2019 May 15;129:227-232
pubmed: 30685303
J Hum Genet. 2013 Apr;58(4):202-9
pubmed: 23364396
Biomed Res Int. 2020 Aug 17;2020:7231243
pubmed: 32879888
Cells. 2019 Nov 30;8(12):
pubmed: 31801236
Cancer Manag Res. 2020 Oct 13;12:10077-10090
pubmed: 33116864
RNA. 2010 Jan;16(1):16-25
pubmed: 19948767
Mol Cancer Ther. 2018 May;17(5):977-987
pubmed: 29545333
J Inflamm Res. 2021 May 05;14:1731-1742
pubmed: 33981152
Cell. 2004 Jan 23;116(2):281-97
pubmed: 14744438
Cancer Chemother Pharmacol. 2006 Nov;58 Suppl 1:s63-8
pubmed: 17093929
Int J Med Sci. 2018 Apr 3;15(6):645-652
pubmed: 29725256
Endocrinology. 2003 Jul;144(7):2870-81
pubmed: 12810542
Oncotarget. 2017 Jun 6;8(23):37225-37238
pubmed: 28402935
Cancer Manag Res. 2020 Aug 24;12:7691-7701
pubmed: 32943920
J Clin Endocrinol Metab. 2019 Jun 1;104(6):1999-2022
pubmed: 30608536
Fertil Steril. 2017 Mar;107(3):537-548
pubmed: 28139239
J Transl Med. 2018 May 21;16(1):131
pubmed: 29783999
Med Sci Monit. 2020 May 03;26:e920611
pubmed: 32361708
Oncol Lett. 2017 Apr;13(4):2053-2058
pubmed: 28454361
Int J Mol Sci. 2016 Jan 13;17(1):
pubmed: 26771608
Oncogene. 2012 May 31;31(22):2750-60
pubmed: 21963845
Geburtshilfe Frauenheilkd. 2017 Jan;77(1):66-72
pubmed: 28190891
Int J Gynaecol Obstet. 2018 Apr;141(1):14-19
pubmed: 29149541