Development and Greenness Assessment of HPLC Method for Studying the Pharmacokinetics of Co-Administered Metformin and Papaya Extract.
RP-HPLC
greenness assessment
metformin
papaya
pharmacokinetics
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
07 Jan 2022
07 Jan 2022
Historique:
received:
07
12
2021
revised:
27
12
2021
accepted:
28
12
2021
entrez:
21
1
2022
pubmed:
22
1
2022
medline:
12
2
2022
Statut:
epublish
Résumé
Foods with medical value have been proven to be beneficial, and they are extensively employed since they integrate two essential elements: food and medication. Accordingly, diabetic patients can benefit from papaya because the fruit is low in sugar and high in antioxidants. An RP-HPLC method was designed for studying the pharmacokinetics of metformin (MET) when concurrently administered with papaya extract. A mobile phase of 0.5 mM of KH
Identifiants
pubmed: 35056687
pii: molecules27020375
doi: 10.3390/molecules27020375
pmc: PMC8778412
pii:
doi:
Substances chimiques
Metformin
9100L32L2N
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deanship of Scientific Research at Jouf University under grant
ID : DSR-2021-01-0305
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