Crab-Eating Monkey Acidic Chitinase (CHIA) Efficiently Degrades Chitin and Chitosan under Acidic and High-Temperature Conditions.

FACE method acidic chitinase chitin chitooligosaccharides chitosan

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
09 Jan 2022
Historique:
received: 19 12 2021
revised: 04 01 2022
accepted: 07 01 2022
entrez: 21 1 2022
pubmed: 22 1 2022
medline: 12 2 2022
Statut: epublish

Résumé

Chitooligosaccharides, the degradation products of chitin and chitosan, possess anti-bacterial, anti-tumor, and anti-inflammatory activities. The enzymatic production of chitooligosaccharides may increase the interest in their potential biomedical or agricultural usability in terms of the safety and simplicity of the manufacturing process. Crab-eating monkey acidic chitinase (CHIA) is an enzyme with robust activity in various environments. Here, we report the efficient degradation of chitin and chitosan by monkey CHIA under acidic and high-temperature conditions. Monkey CHIA hydrolyzed α-chitin at 50 °C, producing

Identifiants

pubmed: 35056724
pii: molecules27020409
doi: 10.3390/molecules27020409
pmc: PMC8781735
pii:
doi:

Substances chimiques

Chitin 1398-61-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Maiko Uehara (M)

Department of Chemistry and Life Science, Kogakuin University, Tokyo 192-0015, Japan.

Chinatsu Takasaki (C)

Department of Chemistry and Life Science, Kogakuin University, Tokyo 192-0015, Japan.

Satoshi Wakita (S)

Department of Chemistry and Life Science, Kogakuin University, Tokyo 192-0015, Japan.

Yasusato Sugahara (Y)

Department of Chemistry and Life Science, Kogakuin University, Tokyo 192-0015, Japan.

Eri Tabata (E)

Department of Chemistry and Life Science, Kogakuin University, Tokyo 192-0015, Japan.
Japan Society for the Promotion of Science (PD), Tokyo 102-0083, Japan.

Vaclav Matoska (V)

Laboratory of Molecular Diagnostics, Department of Clinical Biochemistry, Hematology and Immunology, Homolka Hospital, Roentgenova 37/2, 150 00 Prague, Czech Republic.

Peter O Bauer (PO)

Laboratory of Molecular Diagnostics, Department of Clinical Biochemistry, Hematology and Immunology, Homolka Hospital, Roentgenova 37/2, 150 00 Prague, Czech Republic.
Bioinova JSC, Videnska 1083, 142 20 Prague, Czech Republic.

Fumitaka Oyama (F)

Department of Chemistry and Life Science, Kogakuin University, Tokyo 192-0015, Japan.

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Classifications MeSH