Symmetrical Drug-related Intertriginous and Flexural Exanthema (Baboon Syndrome).

Baboon syndrome amoxicillin penicillin symmetrical drug-related intertriginous and flexural exanthema

Journal

European journal of case reports in internal medicine
ISSN: 2284-2594
Titre abrégé: Eur J Case Rep Intern Med
Pays: Italy
ID NLM: 101648453

Informations de publication

Date de publication:
2021
Historique:
received: 24 10 2021
accepted: 08 11 2021
entrez: 21 1 2022
pubmed: 22 1 2022
medline: 22 1 2022
Statut: epublish

Résumé

Baboon syndrome, also called symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), is an erythematous maculopapular rash that presents in skin folds in a symmetrical pattern. This condition may develop after the patient starts a particular agent. Treatment consists of stopping the associated trigger and medicating with topical or systemic corticosteroids. A 30-year-old man with odynophagia, otalgia and fever was prescribed amoxicillin. He developed erythematous and pruriginous lesions in the cubital fossa and inguinal regions. He attended the emergency department (ED) where he was prescribed penicillin. Lesions continued to progressively worsen with a bilateral symmetrical pattern in the axillary region and later in the nape folds, popliteal regions, and on the perineum and buttocks. The patient presented to the ED for a second time, where he was diagnosed with baboon syndrome and prescribed topical steroids with clear improvement. It is important to identify adverse drug effects.Baboon syndrome is rare and secondary to the use of particular drugs.The diagnosis is based mainly on the patient's clinical presentation.

Identifiants

pubmed: 35059336
doi: 10.12890/2021_003029
pii: 3029-1-25893-1-10-20211201
pmc: PMC8765698
doi:

Types de publication

Journal Article

Langues

eng

Pagination

003029

Informations de copyright

© EFIM 2021.

Déclaration de conflit d'intérêts

Conflicts of Interests: The authors declare there are no competing interests.

Références

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BMJ Case Rep. 2013 Nov 28;2013:
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Auteurs

Olinda Lima Miranda (O)

Internal Medicine Department, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Joao Martins (J)

Internal Medicine Department, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Angela Almeida (A)

Internal Medicine Department, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Mariana Formigo (M)

Internal Medicine Department, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Olga Pereira (O)

Dermatology Department, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Margarida Rocha (M)

Internal Medicine Department, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Jorge Cotter (J)

Internal Medicine Department, Hospital Senhora da Oliveira, Guimaraes, Portugal.

Classifications MeSH