Predicting Risk of Infection After Rhinoplasty with Autogenous Costal Cartilage: A Cohort Study.


Journal

Aesthetic plastic surgery
ISSN: 1432-5241
Titre abrégé: Aesthetic Plast Surg
Pays: United States
ID NLM: 7701756

Informations de publication

Date de publication:
08 2022
Historique:
received: 01 10 2021
accepted: 28 11 2021
pubmed: 22 1 2022
medline: 28 9 2022
entrez: 21 1 2022
Statut: ppublish

Résumé

The study was aimed to develop and validate a nomogram to predict risk of postoperative infection after costal cartilage-based rhinoplasty METHODS: The primary cohort of this study consisted of 672 patients who were appraised between October 2018 and December 2020. The least absolute shrinkage and selection operator (LASSO) regression model was used for data reduction and selection. Multivariable logistic regression analysis was used to develop the predicting model. The calibration curve and C-index were used to evaluate the accuracy of the nomogram, while DCA was used to assess the clinical value. Internal validation was evaluated and an independent validation cohort contained 118 consecutive patients from January 2021 to June 2021. Twenty-one features were reduced to 10 potential predictors on the basis of 672 patients in the primary cohort using LASSO regression. Thus, the predictive nomogram finally contained ten clinical features-age, number of nose operations, length of hospital stay, operation time, history of nose trauma, history of animal contact after operation, smoking after operation in one month, drinking after operation in one month, history of nose infection, and spicy food after operation in one month with the most essential factor. The model showed good discrimination with a C-index of 0.987 (95% CI, 0.978-0.996) (internal validation of 0.967) and good calibration. In addition, the model also had the highest sensitivity due to the AUC of the model was 0.987. Application of the nomogram in the validation cohort still gave good discrimination (C-index, 0.935 [95% CI, 0.910-0.960]). Decision curve analysis demonstrated that the nomogram was clinically helpful. This is the first study to develop a nomogram to predict infection after rhinoplasty with autologous costal cartilage. Use of this nomogram might help surgeons with early identification of patients at high risk of infection. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Identifiants

pubmed: 35059814
doi: 10.1007/s00266-021-02704-7
pii: 10.1007/s00266-021-02704-7
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1797-1805

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021. Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery.

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Auteurs

Xin Wang (X)

Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.

Wenfang Dong (W)

Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.

Huan Wang (H)

Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.

Jianjun You (J)

Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.

Ruobing Zheng (R)

Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.

Yihao Xu (Y)

Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China.

Fei Fan (F)

Department of Rhinoplasty, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No 33, Badachu Road, Shijingshan, Beijing, 100730, People's Republic of China. fanfei@psh.pumc.edu.cn.

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