Previous intravitreal injection as a risk factor of posterior capsule rupture in cataract surgery: a systematic review and meta-analysis.
anti-VEGF
cataract
intravitreal injection
meta-analysis
posterior capsular rupture
systematic review
Journal
Acta ophthalmologica
ISSN: 1755-3768
Titre abrégé: Acta Ophthalmol
Pays: England
ID NLM: 101468102
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
revised:
25
11
2021
received:
31
08
2021
accepted:
29
12
2021
pubmed:
22
1
2022
medline:
12
8
2022
entrez:
21
1
2022
Statut:
ppublish
Résumé
Intravitreal injections and cataract surgery are two common procedures in the elderly. Posterior capsular rupture (PCR) is a rare but important complication of cataract surgery. We systematically reviewed the literature on previous intravitreal injections as a risk factor of PCR and performed meta-analyses to provide pooled summary risk estimates. We searched 13 literature databases on 1 June 2021 for studies evaluating the risk of PCR in eyes undergoing cataract surgery with data on previous intravitreal injections. Data extraction was made independently by two authors and discussed afterwards until reaching consensus. Random effects meta-analyses on the pooled odds ratio (OR) of PCR in eyes with previous intravitreal injections were made using MetaXL 5.3. Six studies on 1 051 097 eyes undergoing cataract surgery were eligible for the qualitative and quantitative review. Previous history of intravitreal injections was present in 7034 eyes (majority was anti-VEGF). Our meta-analyses revealed that any previous intravitreal injection was a risk factor for PCR with an OR of 2.30 (95% CI 1.39-3.81). For each previous intravitreal injection, the risk of PCR was OR 1.04 (95% CI 1.01-1.08) (equivalent of relative risk ~1.04). In other words, risk of PCR increases by 4% for each previous intravitreal injection. Previous intravitreal injection is a risk factor for PCR and should be taken into account when planning cataract surgery. However, to be regarded as a clinically significant risk of PCR, a substantial number of previous intravitreal injection (e.g. ≥10) should have been administered, considering that the a priori risk of PCR is very low (~1%).
Types de publication
Journal Article
Meta-Analysis
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
614-623Informations de copyright
© 2022 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
Références
Allen D & Vasavada A (2006): Cataract and surgery for cataract. BMJ 333: 128-132.
Arbisser LB, Charles S, Howcroft M & Werner L (2006): Management of vitreous loss and dropped nucleus during cataract surgery. Ophthalmol Clin North Am 19: 495-506.
Behndig A, Montan P, Stenevi U, Kugelberg M & Lundström M (2011): One million cataract surgeries: Swedish National Cataract Register 1992-2009. J Cataract Refract Surg 37: 1539-1545.
Bloch SB & Larsen M (2015): Translational public health care perspective: intravitreal treatment of neovascular age-related macular degeneration has revolutionized clinical ophthalmology. Acta Ophthalmol 93: 103-104.
Chakrabarti A & Nazm N (2017): Posterior capsular rent: prevention and management. Indian J Ophthalmol 65: 1359-1369.
Daien V, Le Pape A, Heve D, Carriere I & Villain M (2015): Incidence and characteristics of cataract surgery in France from 2009 to 2012: a national population study. Ophthalmology 122: 1633-1638.
Day AC, Donachie PH, Sparrow JM, Johnston RL & Royal College of Ophthalmologists' National Ophthalmology Database (2015): The Royal College of Ophthalmologists' National Ophthalmology Database Study of cataract surgery: report 2, relationships of axial length with ocular copathology, preoperative visual acuity, and posterior capsule rupture. Eye (Lond) 29: 1528-1537.
Egger M, Davey Smith G, Schneider M & Minder C (1997): Bias in meta-analysis detected by a simple, graphical test. BMJ 315: 629-634.
Gogate PM, Kulkarni SR, Krishnaiah S, Deshpande RD, Joshi SA, Palimkar A & Deshpande MD (2005): Safety and efficacy of phacoemulsification compared with manual small-incision cataract surgery by a randomized controlled clinical trial: six-week results. Ophthalmology 112: 869-874.
Gollogly HE, Hodge DO, St Sauver JL & Erie JC (2013): Increasing incidence of cataract surgery: population-based study. J Cataract Refract Surg 39: 1383-1389.
Hahn P, Jiramongkolchai K, Stinnett S, Daluvoy M & Kim T (2016): Rate of intraoperative complications during cataract surgery following intravitreal injections. Eye (Lond) 30: 1101-1109.
Haripriya A, Chang DF & Ravindran RD (2019): Endophthalmitis reduction with intracameral moxifloxacin in eyes with and without surgical complications: results from 2 million consecutive cataract surgeries. J Cataract Refract Surg 45: 1226-1233.
Higgins J, Thomas J, Chandler J, Cumpston M, Li T, Page M & Welch V (eds) (2021): Cochrane Handbook for Systematic Reviews of Interventions version 6.0 (updated February 2021). Cochrane 2021. Available at: www.training.cochrane.org/handbook. (Accessed on 25 Aug 2021).
Higgins JP, Thompson SG, Deeks JJ & Altman DG (2003): Measuring inconsistency in meta-analyses. BMJ 327: 557-560.
Hård Af Segerstad P (2020): Risk model for intraoperative complication during cataract surgery based on data from 900 000 eyes: previous intravitreal injection is a risk factor. Br J Ophthalmol (ePub ahead of print).
Ianchulev T, Litoff D, Ellinger D, Stiverson K & Packer M (2016): Office-based cataract surgery: population health outcomes study of more than 21 000 cases in the United States. Ophthalmology 123: 723-728.
Jaycock P, Johnston RL, Taylor H et al. (2009): The Cataract National Dataset electronic multi-centre audit of 55,567 operations: updating benchmark standards of care in the United Kingdom and internationally. Eye (Lond) 23: 38-49.
Jun JH, Sohn WJ, Lee Y & Kim JY (2016): Effects of anti-vascular endothelial growth factor monoclonal antibody (bevacizumab) on lens epithelial cells. Clin Ophthalmol 10: 1167-1174.
Keller J & Haynes RJ (2015): Zonular dehiscence at the time of combined vitrectomy and cataract surgery after intravitreal ocriplasmin injection. JAMA Ophthalmol 133: 1091-1092.
Khalifa YM & Pantanelli SM (2011): Quiescent posterior capsule trauma after intravitreal injection: implications for the cataract surgeon. J Cataract Refract Surg 37: 1364.
Kim J, Ryu SY, Hong JH & Chung EJ (2019): Incidence and risk factors for retinal detachment after cataract surgery in Korea: a nationwide population-based study from 2011 to 2015. Graefes Arch Clin Exp Ophthalmol 257: 2193-2202.
Lee AY, Day AC, Egan C et al. (2016): Previous intravitreal therapy is associated with increased risk of posterior capsule rupture during cataract surgery. Ophthalmology 123: 1252-1256.
Lundström M, Behndig A, Kugelberg M, Montan P, Stenevi U & Thorburn W (2011): Decreasing rate of capsule complications in cataract surgery: eight-year study of incidence, risk factors, and data validity by the Swedish National Cataract Register. J Cataract Refract Surg 37: 1762-1767.
Martinez-Enriquez E, Sun M, Velasco-Ocana M, Birkenfeld J, Pérez-Merino P & Marcos S (2016): Optical coherence tomography based estimates of crystalline lens volume, equatorial diameter, and plane position. Invest Ophthalmol Vis Sci 57: OCT600-OCT610.
Miller DC, Christopher KL, Patnaik JL, Lynch AM, Seibold LK, Mandava N & Taravella MJ (2021): Posterior capsule rupture during cataract surgery in eyes receiving intravitreal anti-VEGF injections. Curr Eye Res 46: 179-184.
Moher D, Liberati A, Tetzlaff J, Altman DG & PRISMA Group (2009): Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339: b2535.
Nagar AM, Luis J, Kainth N, Panos GD, Mckechnie CJ & Patra S (2020): The risk of posterior capsule rupture during phacoemulsification cataract surgery in eyes with previous intravitreal anti vascular endothelial growth factor injections. J Cataract Refract Surg (ePub ahead of print).
Narendran N, Jaycock P, Johnston RL et al. (2009): The Cataract National Dataset electronic multicentre audit of 55,567 operations: risk stratification for posterior capsule rupture and vitreous loss. Eye (Lond) 23: 31-37.
Petousis V, Sallam AA, Haynes RJ, Patel CK, Tyagi AK, Kirkpatrick JN & Johnston RL (2016): Risk factors for retinal detachment following cataract surgery: the impact of posterior capsular rupture. Br J Ophthalmol 100: 1461-1465.
Rossi T, Romano MR, Iannetta D, Romano V, Gualdi L, D'Agostino I & Ripandelli G (2021): Cataract surgery practice patterns worldwide: a survey. BMJ Open Ophthalmol 6: e000464.
Saeed MU & Prasad S (2009): Management of cataract caused by inadvertent capsule penetration during intravitreal injection of ranibizumab. J Cataract Refract Surg 35: 1857-1859.
Shalchi Z, Okada M, Whiting C & Hamilton R (2017): Risk of posterior capsule rupture during cataract surgery in eyes with previous intravitreal injections. Am J Ophthalmol 177: 77-80.
Schmidt-Erfurth U, Kaiser PK, Korobelnik JF et al. (2014): Intravitreal aflibercept injection for neovascular age-related macular degeneration: ninety-six-week results of the VIEW studies. Ophthalmology 121: 193-201.
Sparrow JM, Taylor H, Qureshi K, Smith R, Birnie K, Johnston RL & UK EPR User Group (2012): The Cataract National Dataset electronic multi-centre audit of 55,567 operations: risk indicators for monocular visual acuity outcomes. Eye (Lond) 26: 821-826.
Stroup DF, Berlin JA, Morton SC et al. (2000): Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 283: 2008-2012.
Thompson JT (2006): Cataract formation and other complications of intravitreal triamcinolone for macular edema. Am J Ophthalmol 141: 629-637.
Vajpayee RB, Sharma N, Dada T, Gupta V, Kumar A & Dada VK (2001): Management of posterior capsule tears. Surv Ophthalmol 45: 473-488.
Wang W, Yan W, Müller A & He M (2017): A global view on output and outcomes of cataract surgery with national indices of socioeconomic development. Invest Ophthalmol Vis Sci 58: 3669-3676.
Williams GA (2014): IVT Injections: Health Policy Implications. Review of Ophthalmology. Available at: www.reviewofophthalmology.com/article/ivt-injections-health-policy-implications. (Accessed on 25 Aug 2021).
Xu Y & Tan CS (2017): Safety and complications of intravitreal injections performed in an Asian population in Singapore. Int Ophthalmol 37: 325-332.
Zeng X, Zhang Y, Kwong JS, Zhang C, Li S, Sun F, Niu Y & Du L (2015): The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review. J Evid Based Med 8: 2-10.
Ziemssen F, Feltgen N, Holz FG et al. (2017): Demographics of patients receiving Intravitreal anti-VEGF treatment in real-world practice: healthcare research data versus randomized controlled trials. BMC Ophthalmol 17: 7.