Precise Score Validation in Buenos Aires 1 Registry.


Journal

Current problems in cardiology
ISSN: 1535-6280
Titre abrégé: Curr Probl Cardiol
Pays: Netherlands
ID NLM: 7701802

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 23 12 2021
accepted: 03 01 2022
medline: 1 5 2023
pubmed: 23 1 2022
entrez: 22 1 2022
Statut: ppublish

Résumé

The PRECISE-DAPT score predicts the bleeding risk in patients treated with dual antiplatelet treatment after PCI. We asess the prediction power of the score in patients suffering from non-ST elevation acute coronary syndromes. Our cohort included 862 patients from Buenos Aires 1 registry. The PRECISE-DAPT score was calculated upon admission and the follow up period was 15 months. The score as a continuous variable had low to moderate ability to predict bleeding events BARC 2, 3 or 5 (c-statistics 0.58 [95% CI, 0.52-0.61]); moderate at BARC 3 or 5 (c-statistics 0.72 [95% CI, 0.64-0.78]), and poor for MACE (c-statistics 0.49 [95% CI, 0,45-0.51]). PRECISE-DAPT score as a dichotomous variable (≥25, n= 210 [24%]) was associated with very high risk of bleeding (HR 2.1) and ischemic events (HR 1.9, 95% CI 1.8-2.1). As conclusion, PRECISE-DAPT score ≥25 was able to identify a subgroup of patients with high bleeding, and thrombotic events.

Identifiants

pubmed: 35063478
pii: S0146-2806(22)00006-8
doi: 10.1016/j.cpcardiol.2022.101113
pii:
doi:

Substances chimiques

Platelet Aggregation Inhibitors 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101113

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Florencia Muñoz (F)

Ischemic Heart Desease Program of Instituto Cardiovascular (ICBA), Buenos Aires, Argentina.

Marcos Viruel (M)

Ischemic Heart Desease Program of Instituto Cardiovascular (ICBA), Buenos Aires, Argentina.

Cristian Garmendia (C)

Ischemic Heart Desease Program of Instituto Cardiovascular (ICBA), Buenos Aires, Argentina.

Rosina Arbucci (R)

Ischemic Heart Desease Program of Instituto Cardiovascular (ICBA), Buenos Aires, Argentina.

Mirza Rivero (M)

Cardiologist at CEMIC, Buenos Aires, Argentina.

Ernesto Duronto (E)

Cardiologist at Fundación Favaloro de Buenos Aires, Argentina.

Horacio Fernandez (H)

Cardiologist at Hospital Universitario Austral, Buenos Aires, Argentina.

Juan Pablo Costabel (JP)

Ischemic Heart Desease Program of Instituto Cardiovascular (ICBA), Buenos Aires, Argentina. Electronic address: jpcostabel@icba.com.ar.

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Classifications MeSH