Seasonal variation of phenolic compounds in Zostera marina (Zosteraceae) from the Baltic Sea.

Seasonality of natural product contents Sulfated phenolics Zostera marina Zosteraceae

Journal

Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 18 11 2021
revised: 10 01 2022
accepted: 11 01 2022
pubmed: 23 1 2022
medline: 23 2 2022
entrez: 22 1 2022
Statut: ppublish

Résumé

Seasonal variations of phenolic compounds, in leaves of Zostera marina L. from the Baltic Sea near Kiel/Germany were investigated. Dominant compounds were mono- and disulfated flavonoids and phenylpropanoic acids, in particular luteolin 7,3'-O-disulfate and diosmetin 7-O-sulfate as well as rosmarinic acid, a dimeric phenylpropanoid. All detected sulfated flavones showed similar seasonal trends: there were two significant concentration peaks in June and November. Moreover, two geographically distinct flavonoid chemotypes were identified based on their respective main flavonoid; one chemotype was characterized by the prevalence of luteolin 7,3'-O-disulfate (German Baltic Sea), and the other by the prevalence of diosmetin 7-O-sulfate (Norwegian North Sea). Furthermore, an undescribed tetrameric phenylpropanoid, 7'',8''-didehydrosalvianolic acid B, was isolated and its structure was established by extensive NMR, MS, and CD experiments. This compound inhibited activity of Na

Identifiants

pubmed: 35065450
pii: S0031-9422(22)00015-2
doi: 10.1016/j.phytochem.2022.113099
pii:
doi:

Substances chimiques

Phenols 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113099

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Auteurs

Yan Li (Y)

Pharmazeutisches Institut, Abteilung Pharmazeutische Biologie, Christian-Albrechts-Universität zu Kiel, Gutenbergstraße 76, 24118, Kiel, Germany.

Lucie Rárová (L)

Department of Experimental Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-78371, Olomouc, Czech Republic.

Silvia Scarpato (S)

Dipartimento di Farmacia, Università di Napoli Federico II, Via Domenico Montesano 49, 80131, Napoli, Italy.

Serhat Sezai Çiçek (SS)

Pharmazeutisches Institut, Abteilung Pharmazeutische Biologie, Christian-Albrechts-Universität zu Kiel, Gutenbergstraße 76, 24118, Kiel, Germany.

Monica Jordheim (M)

Department of Chemistry, University of Bergen, Allégatan 41, N-5007, Bergen, Norway.

Tereza Štenclová (T)

Department of Experimental Biology, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-78371, Olomouc, Czech Republic.

Miroslav Strnad (M)

Laboratory of Growth Regulators, Faculty of Science, Palacký University, And Institute of Experimental Botany of the Czech Academy of Sciences, Šlechtitelů 27, CZ-78371, Olomouc, Czech Republic.

Alfonso Mangoni (A)

Dipartimento di Farmacia, Università di Napoli Federico II, Via Domenico Montesano 49, 80131, Napoli, Italy.

Christian Zidorn (C)

Pharmazeutisches Institut, Abteilung Pharmazeutische Biologie, Christian-Albrechts-Universität zu Kiel, Gutenbergstraße 76, 24118, Kiel, Germany. Electronic address: czidorn@pharmazie.uni-kiel.de.

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Classifications MeSH