Anorectal Strictures in Complex Perianal CD: How to Approach?
anal canal disease
anal stenosis
proctocolectomy
Journal
Clinics in colon and rectal surgery
ISSN: 1531-0043
Titre abrégé: Clin Colon Rectal Surg
Pays: United States
ID NLM: 101084157
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
entrez:
24
1
2022
pubmed:
25
1
2022
medline:
25
1
2022
Statut:
epublish
Résumé
Anorectal strictures are a notoriously difficult to treat phenotype of perianal Crohn's disease. Quality of life is diminished due to ongoing pain, incontinence, difficulty with stool evacuation, and recurrent medical and surgical treatments. Medical therapy is aimed at treating luminal disease and mucosal ulceration to prevent worsening of fibrosis. Clinical examination and endoscopic intervention can be used for serial dilations of strictures. Unfortunately, despite optimal medical therapy and endoscopic intervention with serial anal dilations, surgery with intestinal diversion or proctocolectomy may be required as part of the treatment algorithm in a significant proportion of patients.
Identifiants
pubmed: 35069029
doi: 10.1055/s-0041-1740037
pii: 01122
pmc: PMC8763464
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
44-50Informations de copyright
Thieme. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of Interest A.L.L. is a consultant for Takeda. M.R. is a consultant for Abbvie, Janssen, UCB, Takeda, Pfizer, Miraca Labs, Amgen, Celgene, Seres, Allergan, Genentech, Gilead, Salix, Prometheus, Lilly, TARGET Pharma Solutions, ALFASIGMA, S.p.A., Bristol Meyer Squibb (BMS). M.R. reports other from Pfizer, other from Takeda, other from Janssen, other from Abbvie, outside the submitted work. A.L.L. reports personal fees from Takeda, outside the submitted work.
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