Trends of alcoholic liver cirrhosis readmissions from 2010 to 2018: Rates and healthcare burden associated with readmissions.
Alcoholic liver cirrhosis
Epidemiology
Mortality
Readmissions
Trends
Journal
World journal of hepatology
ISSN: 1948-5182
Titre abrégé: World J Hepatol
Pays: United States
ID NLM: 101532469
Informations de publication
Date de publication:
27 Dec 2021
27 Dec 2021
Historique:
received:
29
06
2021
revised:
24
08
2021
accepted:
15
11
2021
entrez:
24
1
2022
pubmed:
25
1
2022
medline:
25
1
2022
Statut:
ppublish
Résumé
Alcoholic liver cirrhosis (ALC) is a chronic liver disease with varying disease severity. Readmissions of ALC are associated with poor outcomes. To identify and assess trends of readmissions for ALC over an eight-year period. This retrospective interrupted trend study analysed 30-d readmissions of ALC in the United States from 2010 to 2018 using the National Readmissions Database. Hospitalization for ALC was the reason for index admission obtained using the International Classification of Diseases codes (571.2 and K70.3X). Biodemographic characteristics and hospitalization trends were highlighted over time. A multivariate regression analysis model was used to calculate the trend for risk-adjusted odds of 30-d all-cause ALC readmissions, ALC specific readmission rate, ALC readmission proportion, inpatient mortality, mean length of stay (LOS) and mean total hospital cost (THC) following adjustments for age, gender, grouped Charlson Comorbidity Index, insurance, mean household income, and hospital characteristics. There was a trend towards increasing total 30-d readmissions of ALC from 7660 in 2010 to 15085 in 2018 ( There was an increase in the 30-d readmission rate and comorbidity burden for ALC; however, inpatient mortality declined. Additionally, there was a trend towards increasing LOS and THC for these readmissions.
Sections du résumé
BACKGROUND
BACKGROUND
Alcoholic liver cirrhosis (ALC) is a chronic liver disease with varying disease severity. Readmissions of ALC are associated with poor outcomes.
AIM
OBJECTIVE
To identify and assess trends of readmissions for ALC over an eight-year period.
METHODS
METHODS
This retrospective interrupted trend study analysed 30-d readmissions of ALC in the United States from 2010 to 2018 using the National Readmissions Database. Hospitalization for ALC was the reason for index admission obtained using the International Classification of Diseases codes (571.2 and K70.3X). Biodemographic characteristics and hospitalization trends were highlighted over time. A multivariate regression analysis model was used to calculate the trend for risk-adjusted odds of 30-d all-cause ALC readmissions, ALC specific readmission rate, ALC readmission proportion, inpatient mortality, mean length of stay (LOS) and mean total hospital cost (THC) following adjustments for age, gender, grouped Charlson Comorbidity Index, insurance, mean household income, and hospital characteristics.
RESULTS
RESULTS
There was a trend towards increasing total 30-d readmissions of ALC from 7660 in 2010 to 15085 in 2018 (
CONCLUSION
CONCLUSIONS
There was an increase in the 30-d readmission rate and comorbidity burden for ALC; however, inpatient mortality declined. Additionally, there was a trend towards increasing LOS and THC for these readmissions.
Identifiants
pubmed: 35070013
doi: 10.4254/wjh.v13.i12.2128
pmc: PMC8727209
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2128-2136Informations de copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors have no financial relationships or conflict-of-interests to disclose.
Références
J Hepatol. 2021 Jun;74(6):1286-1294
pubmed: 33326815
Hepatology. 2018 Sep;68(3):872-882
pubmed: 29579356
World J Gastroenterol. 2014 Jun 21;20(23):7223-30
pubmed: 24966593
World J Hepatol. 2012 Mar 27;4(3):81-90
pubmed: 22489260
Clin Gastroenterol Hepatol. 2016 Aug;14(8):1181-1188.e2
pubmed: 27085758
Health Serv Res. 2018 Feb;53(1):175-196
pubmed: 27873305
Dig Dis Sci. 2019 Jun;64(6):1460-1469
pubmed: 30673984
JAMA Psychiatry. 2017 Sep 1;74(9):911-923
pubmed: 28793133
Postgrad Med J. 2000 May;76(895):280-6
pubmed: 10775280
J Hosp Med. 2018 Apr 25;:
pubmed: 29694458
Alcohol Res. 2020 Jul 30;40(2):08
pubmed: 32742894
J Hepatol. 2012 May;56(5):1054-1062
pubmed: 22245890
Med Care. 2007 Dec;45(12):1210-5
pubmed: 18007172