Therapeutic innovation for multi-resistant candidemics: Synergy of isavuconazole and caspofungin association.
Candida
Caspofungin
Combined antifungal therapy
Fungal infection
Hematological patients
Isavuconazole
Journal
Hematology reports
ISSN: 2038-8322
Titre abrégé: Hematol Rep
Pays: Switzerland
ID NLM: 101556723
Informations de publication
Date de publication:
26 Nov 2021
26 Nov 2021
Historique:
received:
22
07
2021
accepted:
17
09
2021
entrez:
24
1
2022
pubmed:
25
1
2022
medline:
25
1
2022
Statut:
epublish
Résumé
Fungal infections occurring in immunocompromised patients after immunochemotherapy treatment are often difficult to eradicate and capable of even being fatal. Systemic mycoses affecting severely immunocompromised patients often manifest acutely with rapidly progressive pneumonia, fungemia, or manifestations of extrapulmonary dissemination. Opportunistic fungal infections (mycoses) include several pathogens elements, as candidiasis, aspergillosis, mucormycosis (zygomycosis) and fusariosis. Prompt diagnosis and effective therapy are needed to improve the associated morbidity and mortality, especially in cases with non-canonical fungal localizations and not responsive to the available antifungal drugs.
Identifiants
pubmed: 35070221
doi: 10.4081/hr.2021.9329
pmc: PMC8743983
doi:
Types de publication
Journal Article
Langues
eng
Pagination
9329Informations de copyright
©Copyright: the Author(s).
Déclaration de conflit d'intérêts
Conflict of interest: The authors declare no potential conflict of interest.
Références
Pharmacotherapy. 2007 Dec;27(12):1711-21
pubmed: 18041891
J Ophthalmol. 2020 Oct 23;2020:8869590
pubmed: 33149945
Curr Eye Res. 2017 Feb;42(2):225-232
pubmed: 27348425
Ocul Immunol Inflamm. 2020 Apr 2;28(3):471-478
pubmed: 30810429
Antimicrob Agents Chemother. 2017 Dec 21;62(1):
pubmed: 29038263
Am J Ophthalmol. 2012 Jan;153(1):162-6.e1
pubmed: 21917234
Klin Mikrobiol Infekc Lek. 2009 Apr;15(2):48-57
pubmed: 19488961
Med Mycol. 2021 Oct 4;59(10):1015-1023
pubmed: 34021571
Haematologica. 2012 Apr;97(4):560-7
pubmed: 22102706
Br J Ophthalmol. 2008 Apr;92(4):466-8
pubmed: 18369061