Laparoscopic

intrahepatic cholangiocarcinoma laparoscopic hepatectomy liver resection overall survival recurrence-free survival

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2021
Historique:
received: 16 07 2021
accepted: 08 12 2021
entrez: 24 1 2022
pubmed: 25 1 2022
medline: 25 1 2022
Statut: epublish

Résumé

Surgical resection is the only widely accepted curative method for intrahepatic cholangiocarcinoma (ICC). However, little is known about the efficacy of laparoscopic liver resection for ICC, especially in patients with early-stage disease. The aim of this study was to compare the short-term and long-term effects of laparoscopy and open surgery for the treatment of ICC. Data from 1,084 patients treated at three hospitals from January 2011 to December 2018 were selected and analyzed. Propensity score matching was performed to compare the long-term outcomes (overall survival and recurrence-free survival) and short-term outcomes (perioperative outcomes) of all-stage and early-stage patients. After matching, 244 patients (122 Patients treated with laparoscopy seemed to have better short-term outcomes, such as less blood loss, shorter operation duration, and shorter hospital stay, than patients undergoing open surgery. Based on the long-term results, laparoscopic treatment for early ICC may have certain advantages.

Sections du résumé

BACKGROUND BACKGROUND
Surgical resection is the only widely accepted curative method for intrahepatic cholangiocarcinoma (ICC). However, little is known about the efficacy of laparoscopic liver resection for ICC, especially in patients with early-stage disease. The aim of this study was to compare the short-term and long-term effects of laparoscopy and open surgery for the treatment of ICC.
METHODS METHODS
Data from 1,084 patients treated at three hospitals from January 2011 to December 2018 were selected and analyzed. Propensity score matching was performed to compare the long-term outcomes (overall survival and recurrence-free survival) and short-term outcomes (perioperative outcomes) of all-stage and early-stage patients.
RESULTS RESULTS
After matching, 244 patients (122
CONCLUSION CONCLUSIONS
Patients treated with laparoscopy seemed to have better short-term outcomes, such as less blood loss, shorter operation duration, and shorter hospital stay, than patients undergoing open surgery. Based on the long-term results, laparoscopic treatment for early ICC may have certain advantages.

Identifiants

pubmed: 35070961
doi: 10.3389/fonc.2021.742544
pmc: PMC8777042
doi:

Types de publication

Journal Article

Langues

eng

Pagination

742544

Informations de copyright

Copyright © 2022 Jinhuan, Yi, Yuanwen, Delin, Xiaotian, Yan, Liming, Haitao, Lijun, Tuo, Kaiyu, Jiawei, Chongming, Daojie, Bin and Gang.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Yang Jinhuan (Y)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Wang Yi (W)

Department of Epidemiology and Biostatistics, School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.

Zheng Yuanwen (Z)

Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Jinan, China.

Ma Delin (M)

Department of Hepatobiliary Surgery, Qilu Hospital of Shandong University, Jinan, China.

Chen Xiaotian (C)

Department of Clinical Medicine, The Second School of Medicine, Wenzhou Medical University, Wenzhou, China.

Wang Yan (W)

Department of Clinical Medicine, The Second School of Medicine, Wenzhou Medical University, Wenzhou, China.

Deng Liming (D)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Yu Haitao (Y)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Wu Lijun (W)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Deng Tuo (D)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Chen Kaiyu (C)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Hu Jiawei (H)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Zheng Chongming (Z)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Wang Daojie (W)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Jin Bin (J)

Department of Hepatobiliary Surgery, Qilu Hospital of Shandong University, Jinan, China.

Chen Gang (C)

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Classifications MeSH