The Kidney Failure Risk Equation Score and CKD Care Delivery Measures: A Cross-sectional Study.

Chronic kidney disease kidney failure risk equation quality improvement urine albumin/creatinine ratio

Journal

Kidney medicine
ISSN: 2590-0595
Titre abrégé: Kidney Med
Pays: United States
ID NLM: 101756300

Informations de publication

Date de publication:
Jan 2022
Historique:
entrez: 24 1 2022
pubmed: 25 1 2022
medline: 25 1 2022
Statut: epublish

Résumé

The 4-variable kidney failure risk equation (KFRE) allows for the prediction of chronic kidney disease (CKD) progression using age, sex, estimated glomerular filtration rate, and urine albumin/creatinine ratio. Electronic health records enable KFRE auto-calculation, and registries allow population-level application. We assessed whether 2-year KFRE score categories are associated with CKD care metrics. Cross-sectional cohort. This study included individuals with CKD in March 2020 who were receiving care within the Partners HealthCare system in Massachusetts. The presence of sufficient data to calculate the KFRE and, among those with a KFRE score, performance on CKD clinical care metrics, including (1) prescription of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker; (2) blood pressure at goal (<140/90 mm Hg) based on clinic measurements; (3) composite metric of hepatitis B virus immunity; (4) composite metric of referral, evaluation, or waitlist status for kidney transplantation; (5) advance directive documentation; (6) yearly influenza vaccination; and (7) pneumonia vaccination. Multivariable logistic regression analysis was used to analyze the association of KFRE score category with CKD care metrics. Of 61,546 patients, 18,272 (30%) had auto-calculated 2-year KFRE scores; the remaining patients lacked KFRE scores because of absent albuminuria assessment. Individuals with a KFRE score were more likely to have a primary care provider or nephrologist. Among patients with 2-year KFRE scores, high-risk patients had increased odds of completing advance directives (OR, 1.52; 95% CI, 1.07-2.17), while low-risk patients had decreased odds of influenza vaccination (OR, 0.85; 95% CI, 0.75-0.97). Patients with moderate- and high-risk KFRE scores had lower odds of having blood pressure at goal (OR, 0.77; 95% CI, 0.61-0.96 and OR, 0.63; 95% CI, 0.44-0.88, respectively). Albuminuria data may have been assessed outside of the Partners system. A higher-risk KFRE score is associated with the delivery of some but not all CKD care measures. An opportunity exists to improve albuminuria measurement.

Identifiants

pubmed: 35072040
doi: 10.1016/j.xkme.2021.08.010
pii: S2590-0595(21)00218-1
pmc: PMC8767093
doi:

Types de publication

Journal Article

Langues

eng

Pagination

100375

Informations de copyright

© 2021 The Authors.

Références

Am J Kidney Dis. 1997 Apr;29(4):533-40
pubmed: 9100041
JAMA Netw Open. 2019 Dec 2;2(12):e1918169
pubmed: 31860111
JAMA. 2011 Apr 20;305(15):1553-9
pubmed: 21482743
Am J Kidney Dis. 2004 May;43(5 Suppl 1):S1-290
pubmed: 15114537
Nephrol Dial Transplant. 2017 May 1;32(5):748-751
pubmed: 28499025
Clin J Am Soc Nephrol. 2008 Jan;3(1):226-36
pubmed: 18003763
JAMA. 2016 Jan 12;315(2):164-74
pubmed: 26757465
Can J Kidney Health Dis. 2019 May 29;6:2054358119841611
pubmed: 31191908
Nephrol Dial Transplant. 2005 Jan;20(1):147-54
pubmed: 15585514
PLoS Med. 2019 Nov 6;16(11):e1002955
pubmed: 31693662
BMJ Open. 2019 Jun 9;9(6):e027315
pubmed: 31182446
Lancet. 2019 Jan 5;393(10166):31-39
pubmed: 30424892
Can J Kidney Health Dis. 2017 Aug 09;4:2054358117722782
pubmed: 28835850
J Am Soc Nephrol. 2009 Sep;20(9):2075-84
pubmed: 19608703
Clin J Am Soc Nephrol. 2014 Sep 5;9(9):1526-35
pubmed: 25135764
J Am Soc Nephrol. 2004 Jan;15 Suppl 1:S58-63
pubmed: 14684675
BMC Nephrol. 2019 Mar 1;20(1):72
pubmed: 30823871
Lancet. 2020 Feb 29;395(10225):709-733
pubmed: 32061315
JAMA Netw Open. 2019 Sep 4;2(9):e1910704
pubmed: 31483474
Perm J. 2017;21:16-143
pubmed: 28241912
Am J Kidney Dis. 2018 Aug;72(2):168-177
pubmed: 29699885

Auteurs

Salman Ahmed (S)

Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Suraj Sarvode Mothi (SS)

Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Thomas Sequist (T)

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Quality and Safety, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Partners HealthCare, Department of Quality, Patient Experience and Equity, Boston, MA.

Navdeep Tangri (N)

Chronic Disease Innovation Centre, Seven Oaks General Hospital, Winnipeg, Manitoba, Canada.

Roaa M Khinkar (RM)

Department of Quality and Safety, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Pharmacy Practice, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.

Mallika L Mendu (ML)

Division of Renal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Department of Quality and Safety, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Partners HealthCare, Center for Population Health, Boston, MA.

Classifications MeSH