Response to American College of Physician's statement on the ethics of transplant after normothermic regional perfusion.

donors and donation: donation after circulatory death editorial/personal viewpoint ethics ethics and public policy law/legislation organ perfusion and preservation organ procurement organ procurement and allocation organ transplantation in general

Journal

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
ISSN: 1600-6143
Titre abrégé: Am J Transplant
Pays: United States
ID NLM: 100968638

Informations de publication

Date de publication:
05 2022
Historique:
revised: 27 12 2021
received: 04 10 2021
accepted: 28 12 2021
pubmed: 25 1 2022
medline: 11 5 2022
entrez: 24 1 2022
Statut: ppublish

Résumé

This paper responds to the position statement released by the American College of Physicians (ACP) entitled "Ethics, Determination of Death, and Organ Transplantation in Normothermic Regional Perfusion (NRP) with Controlled Donation after Circulatory Determination of Death (cDCD): American College of Physicians Statement of Concern." The ACP's statement engages with critical ethical issues surrounding cDCD NRP, but several of their conclusions are flawed. Contrary to the statement, the practice respects the dead donor rule and the legal definition of death while honoring the wishes of the deceased and their loved ones to help save the lives of those in need of organ transplants. cDCD NRP is well established in many countries, it can enhance trust in medical practice and organ donation, and will increase the availability of optimal organs for life-saving transplants.

Identifiants

pubmed: 35072337
doi: 10.1111/ajt.16947
pii: S1600-6135(22)08200-4
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1307-1310

Commentaires et corrections

Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : CommentIn
Type : CommentIn

Informations de copyright

© 2022 The American Society of Transplantation and the American Society of Transplant Surgeons.

Références

American College of Physicians. Ethics, determination of death, and organ transplantation in normothermic regional perfusion (NRP) with controlled donation after circulatory determination of death (cDCD): American College of Physicians Statement of Concern. https://www.acponline.org/acp_policy/policies/ethics_determination_of_death_and_organ_transplantation_in_nrp_2021.pdf. Published 2021. Accessed January 12, 2022.
Jochmans I, Hessheimer AJ, Neyrinck AP, et al. Consensus statement on normothermic regional perfusion in donation after circulatory death: report from the European Society for organ transplantation’s transplant learning journey. Transpl Int. 2021. 10.1111/tri.13951
Parent B, Moazami N, Wall S, et al. Ethical and logistical concerns for establishing NRP-cDCD heart transplantation in the United States. Am J Transplant. 2020;20(6):1508-1512.
Point BJL. Are donors after circulatory death really dead, and does it matter? Yes and yes. Chest. 2010;138(1):13-16. 10.1378/chest.10-0649
Parent B, Turi A. Death’s troubled relationship with the law. AMA J Ethics. 2020;22(12):1055-1061.
Lewis A, Bonnie RJ, Pope T, et al. Determination of death by neurologic criteria in the United States: the case for revising the uniform determination of death act. J Law Med Ethics. 2019 (suppl 4):9-24.
Manara A, Shemie SD, Large S, et al. Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: a United Kingdom and Canadian proposal. Am J Transplant. 2020;20(8):2017-2025.
Messer S, Cernic S, Page A, et al. A 5-year single-center early experience of heart transplantation from donation after circulatory-determined death donor. J Heart Lung Transpl. 2020;39(12):1463-1475.
Page A, Messer S, Large S. Heart transplantation from donation after circulatory determined death. Ann Cardiothoracic Surg. 2018;7(1):75-81.
Tsui SS, Oniscu GC. Extending normothermic regional perfusion to the thorax in donors after circulatory death. Curr Opin Organ Transplant. 2017;22(3):245-250.

Auteurs

Brendan Parent (B)

Division of Medical Ethics, NYU Grossman School of Medicine, New York, New York.

Arthur Caplan (A)

Division of Medical Ethics, NYU Grossman School of Medicine, New York, New York.

Nader Moazami (N)

NYU Langone Medical Center, Transplant Institute, New York, New York.

Robert A Montgomery (RA)

NYU Langone Medical Center, Transplant Institute, New York, New York.

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