Alpha particle
LET radiation
RBE
radiosensitivity
Journal
International journal of radiation biology
ISSN: 1362-3095
Titre abrégé: Int J Radiat Biol
Pays: England
ID NLM: 8809243
Informations de publication
Date de publication:
2022
2022
Historique:
pubmed:
25
1
2022
medline:
3
9
2022
entrez:
24
1
2022
Statut:
ppublish
Résumé
In the current work, the RBE of a Mammary carcinoma NT2.5 cells were treated with (0-3.70) kBq/ml of radiolabeled antibody. Nonspecific binding was assessed with addition of excess amount of unlabeled antibody. The colony formation curves were converted from activity concentration to cell nucleus absorbed dose by simulating the decay and transport of all daughter and secondary particles of The radiolabeled antibody yielded an RBE of 8.3 at 37% survival and a survival independent RBE (i.e. RBE2) of 9.9. Unbound/untargeted
Identifiants
pubmed: 35073214
doi: 10.1080/09553002.2022.2033341
pmc: PMC9673603
mid: NIHMS1846375
doi:
Substances chimiques
Lead
2P299V784P
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1452-1461Subventions
Organisme : NCI NIH HHS
ID : R01 CA116477
Pays : United States
Commentaires et corrections
Type : ErratumIn
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