Daytime urotherapy in nocturnal enuresis: a randomised, controlled trial.
enuresis
nephrology
paediatrics
Journal
Archives of disease in childhood
ISSN: 1468-2044
Titre abrégé: Arch Dis Child
Pays: England
ID NLM: 0372434
Informations de publication
Date de publication:
06 2022
06 2022
Historique:
received:
03
11
2021
accepted:
03
01
2022
pubmed:
26
1
2022
medline:
24
5
2022
entrez:
25
1
2022
Statut:
ppublish
Résumé
According to international guidelines, children with enuresis are recommended urotherapy, or basic bladder advice, before treatment with evidence-based alternatives such as the enuresis alarm is given. The efficacy of this strategy has, however, not been supported by controlled studies. We wanted to test if basic bladder advice is useful in enuresis. Randomised, controlled trial. Paediatric outpatient ward, regional hospital. Treatment-naïve enuretic children aged ≥6 years, with no daytime incontinence. Three groups, each during 8 weeks: (A) basic bladder advice-that is, voiding and drinking according to a strict schedule and instructions regarding toilet posture, (B) enuresis alarm therapy and (C) no treatment (control group). Reduction in enuresis frequency during week 7-8 compared with baseline. The median number of wet nights out of 14 before and at the end of treatment were in group A (n=20) 12.5 and 11.5 (p=0.44), in group B (n=22) 11.0 and 3.5 (p<0.001) and in group C (n=18) 12.5 and 12.0 (p=0.55). The difference in reduction of enuresis frequency between the groups was highly significant (p=0.002), but no difference was found between basic bladder advice and controls. Urotherapy, or basic bladder advice, is ineffective as a first-line treatment of nocturnal enuresis. Enuretic children who are old enough to be bothered by their condition should be offered treatment with the alarm or desmopressin. NCT03812094.
Identifiants
pubmed: 35074830
pii: archdischild-2021-323488
doi: 10.1136/archdischild-2021-323488
pmc: PMC9125372
doi:
Banques de données
ClinicalTrials.gov
['NCT03812094']
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
570-574Informations de copyright
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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