Evaluation of exposure to secondhand smoke and serum level of interleukin 18 in non-smokers.
Global health
Inflammation
Interleukin-18
Pollution
Smoke
Tobacco
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
26
10
2021
revised:
29
12
2021
accepted:
31
12
2021
entrez:
26
1
2022
pubmed:
27
1
2022
medline:
27
1
2022
Statut:
epublish
Résumé
Smoking is one significant global health care problems, that not only affects the users but also endangers the health of people inhaling the smoke (passive smoking/secondhand smoke). The serum level of IL-18, an important regulator of inherent and acquired immune response, is affected by cigarette smoking. The aim of this study was to evaluate the effect of secondhand smoke (SHS) exposure on IL-18 serum level in non-smoker adults. In a case-control study, using easy sampling method, 76 non-smokers who were exposed to cigarette smoke for at least 1 h daily during the past year were considered as exposure group, while 76 of their companions without exposure to cigarette smoke (after matching age) were considered as non-exposure group. Serum IL-18 levels were measured for all participants and finally compared between the two groups using Chi-square test. P value < 0.05 was considered to be statistically significant. The exposure and non-exposure groups included 58 (76.3%) and 25 (32.9%) males, respectively ( The exposure to secondhand smoke has no significant effect on serum level of IL-18 in exposed adult individuals. However, more studies with larger sample sizes on different populations are required to confirm these results.
Identifiants
pubmed: 35079372
doi: 10.1016/j.amsu.2021.103238
pii: S2049-0801(21)01188-2
pmc: PMC8767295
doi:
Types de publication
Journal Article
Langues
eng
Pagination
103238Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
The authors deny any conflict of interest in any terms or by any means during the study. All the fees provided by research center fund and deployed accordingly.
Références
Am J Clin Nutr. 2006 Feb;83(2):447S-455S
pubmed: 16470011
Allergy Asthma Proc. 2004 May-Jun;25(3):181-4
pubmed: 15317323
Am J Respir Cell Mol Biol. 2013 Jun;48(6):725-32
pubmed: 23392573
Toxicol Mech Methods. 2017 Jul;27(6):458-466
pubmed: 28413934
Am J Respir Crit Care Med. 2009 Jun 1;179(11):1029-33
pubmed: 19264972
Immunity. 2015 Mar 17;42(3):566-79
pubmed: 25786179
Occup Environ Med. 2001 Sep;58(9):563-8
pubmed: 11511742
Genes Immun. 2007 Mar;8(2):91-9
pubmed: 17215860
J Biol Chem. 2001 Oct 5;276(40):37069-75
pubmed: 11477102
Drug News Perspect. 2007 Oct;20(8):485-94
pubmed: 18080035
BMC Public Health. 2015 Oct 14;15:1053
pubmed: 26468075
Chest. 2002 Sep;122(3):1086-90
pubmed: 12226059
Lung. 2007 May-Jun;185(3):161-71
pubmed: 17436040
Inhal Toxicol. 2017 Jul;29(8):366-373
pubmed: 29039230
Am J Respir Crit Care Med. 2012 Jun 1;185(11):1205-17
pubmed: 22383501
Atherosclerosis. 2010 Feb;208(2):550-6
pubmed: 19700161
J Immunol. 2018 Apr 15;200(8):2927-2940
pubmed: 29555783
Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2256-61
pubmed: 10051628
J Immunol. 2007 Feb 1;178(3):1948-59
pubmed: 17237446
Ann Med Surg (Lond). 2021 Nov 06;72:103026
pubmed: 34820121
PLoS One. 2014 Nov 18;9(11):e112829
pubmed: 25405768
Arch Iran Med. 2020 Jun 01;23(6):369-377
pubmed: 32536173
Lancet. 2011 Jan 8;377(9760):139-46
pubmed: 21112082
Am J Respir Cell Mol Biol. 2008 Feb;38(2):218-26
pubmed: 17872497
Int J Mol Sci. 2017 Mar 17;18(3):
pubmed: 28304347
Respir Med. 2009 Dec;103(12):1919-25
pubmed: 19539457
PLoS One. 2017 Mar 31;12(3):e0174541
pubmed: 28362801
Chest. 2015 Jul;148(1):112-119
pubmed: 25742439
J Clin Invest. 2008 Aug;118(8):2771-84
pubmed: 18654661
J Immunol. 2001 Dec 1;167(11):6568-75
pubmed: 11714826
J Investig Med. 2001 Jan;49(1):21-9
pubmed: 11217144
J Immunol. 2001 Dec 15;167(12):7060-8
pubmed: 11739527
Environ Health Perspect. 2000 Jan;108(1):73-82
pubmed: 10620527