Biodegradation and Immunological Parameters of Polyurethane-Based Tissue Adhesive in Arterial Microvascular Anastomoses-A Long-Term In Vivo Study.
adhesive
biodegradation
microsurgery
tissue compatibility
Journal
Macromolecular bioscience
ISSN: 1616-5195
Titre abrégé: Macromol Biosci
Pays: Germany
ID NLM: 101135941
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
revised:
16
01
2022
received:
08
11
2021
pubmed:
27
1
2022
medline:
19
4
2022
entrez:
26
1
2022
Statut:
ppublish
Résumé
In microsurgical anastomosis, non-synthetic fibrin-based adhesives have predominantly shown superior properties to synthetic cyanoacrylates, but they have hardly any clinical application. This study aims to investigate the local and systemic effects of synthetically produced biodegradable adhesive VIVO when used in microsurgical anastomosis. VIVO is used in two different anastomosis procedures in the common carotid artery in a rat model: VIVO in addition to a temporary catheter (VIVO TC) and VIVO with a custom-shaped memory nitinol stent (VIVO SM). Conventionally sutured anastomoses serve as controls (C). Tissue response is assessed by in vivo fluorescence imaging and histological examination. The systemic effects of biodegradation are measured using hematologic parameters and serum levels of transaminase activity and lactate dehydrogenase. Finally, the degree of local adhesion of the different anastomotic procedures is evaluated. Fluorescence imaging shows reduced inflammatory blood flow in the VIVO TC group. Histological analysis of the anastomosed vessels also reveals significantly more inflammation in C than in the two adhesive groups. The severity of VIVO adhesions proves acceptable, and no histotoxic effects of VIVO are detected. The data demonstrate that the synthetic tissue adhesive VIVO is a reliable and-compared to sutures-tissue-friendly adhesive for microsurgical anastomoses.
Identifiants
pubmed: 35080346
doi: 10.1002/mabi.202100451
doi:
Substances chimiques
Adhesives
0
Fibrin Tissue Adhesive
0
Polyurethanes
0
Tissue Adhesives
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2100451Informations de copyright
© 2022 The Authors. Macromolecular Bioscience published by Wiley-VCH GmbH.
Références
E. I. Chang, M. G. Galvez, J. P. Glotzbach, C. D. Hamou, S. El-Ftesi, C. T. Rappleye, K.-M. Sommer, J. Rajadas, O. J. Abilez, G. G. Fuller, M. T. Longaker, G. C. Gurtner, Nat. Med. 2011, 17, 1147.
M. Ziche, L. Morbidelli, E. Masini, S. Amerini, H. J. Granger, C. A. Maggi, P. Geppetti, F. Ledda, J. Clin. Invest. 1994, 94, 2036.
Y.-X. Chen, L.-E. Chen, A. V. Seaber, J. R. Urbaniak, J. Hand Surg. 2001, 26, 530.
S. K. Mudigonda, S. Murugan, K. Velavan, S. Thulasiraman, V. B. K. K. Raja, J. Craniomaxillofacial Surg. 2020, 48, 599.
X. Liang, S. Liu, Z. Fang, G. Sun, Z. Guo, J. Craniofacial Surg. 2019, 30, 74.
L. M. Ritschl, A. M. Fichter, M. Von Düring, D. A. Mitchell, K.-D. Wolff, T. Mücke, Plast. Reconstr. Surg. 2015, 136, 1216.
W. G. Middleton, W. Matthews, D. A. Chiasson, J. Otolaryngol. 1991, 20, 363.
D. Lemaire, J. Mongeau, D. Dorion, J. Otolaryngol. 2000, 29, 199.
R. M. Pearl, K. Wustrack, C. Harbury, E. Rubenstein, E. Kaplan, Surg., Gynecol. Obstet. 1977, 144, 227.
T. Matsumoto, Arch. Surg. 1967, 94, 858.
T. Mücke, K.-D. Wolff, Microsurgery 2009, 29, 80.
M. Kawamura, M. Sawafuji, M. Watanabe, H. Horinouchi, K. Kobayashi, Ann. Thorac. Surg. 2002, 73, 1098.
A. B. Cho, R. M. Junior, Plast. Reconstr. Surg. 2007, 119, 95.
J. M. Albes, C. Krettek, B. Hausen, R. Rohde, A. Haverich, H.-G. Borst, Ann. Thorac. Surg. 1993, 56, 910.
H. Tanaka, K. Fukushima, P. K. Srinivasan, K. Pawlowsky, B. Koegel, K. Hata, Y. Ku, S. Uemoto, R. H. Tolba, Surg. Innovation 2017, 24, 423.
K. Fukushima, H. Tanaka, P. K. Srinivasan, K. Pawlowsky, B. Kögel, S. Uemoto, Y. Ku, R. H. Tolba, Eur. Surg. Res. 2018, 59, 48.
M. Heitzer, J. Brockhaus, K. Kniha, F. Merkord, F. Peters, F. Holzle, E. Goloborodko, A. Modabber, Sci. Rep. 2021, 11, 13598.
M. Heitzer, S. C. Mohlhenrich, K. Kniha, R. Tolba, S. Jockenhoevel, F. Holzle, A. Modabber, Ann. Anat. 2021, 238, 151782.
B. B. Sheppard, C. De Virgilio, M. Bleiweis, J. C. Milliken, J. M. Robertson, Am. Surg. 1993, 59, 786.
C. Indolfi, A. Mongiardo, A. Curcio, D. Torella, Trends Cardiovasc. Med. 2003, 13, 142.
A. Farzin, A. K. Miri, F. Sharifi, N. Faramarzi, A. Jaberi, A. Mostafavi, R. Solorzano, Y. S. Zhang, N. Annabi, A. Khademhosseini, A. Tamayol, Adv. Healthcare Mater. 2018, 7, 1800702.
C. R. Davis, C. T. Rappleye, P. A. Than, M. Rodrigues, M. W. Findlay, S. N. Bishop, A. J. Whitmore, Z. N. Maan, R. B. Mcgoldrick, A. O. Grobbelaar, G. C. Gurtner, Plast. Reconstr. Surg. 2016, 137, 546.
T. Aizawa, M. Kuwabara, S. Kubo, T. Domoto, S. Aoki, R. Azuma, T. Kiyosawa, J. Reconstr. Microsurg. 2018, 34, 8.
Q. Ma, X. Shi, X. Tan, R. Wang, K. Xiong, M. F. Maitz, Y. Cui, Z. Hu, Q. Tu, N. Huang, L. Shen, Z. Yang, Bioact. Mater. 2021, 6, 4786.
P. K. Bowen, E. R. Shearier, S. Zhao, R. J. Guillory II, F. Zhao, J. Goldman, J. W. Drelich, Adv. Healthcare Mater. 2016, 5, 1121.
F. Migliavacca, L. Petrini, P. Massarotti, S. Schievano, F. Auricchio, G. Dubini, Biomech. Model. Mechanobiol 2004, 2, 205.
R. S. Schwartz, K. C. Huber, J. G. Murphy, W. D. Edwards, A. R. Camrud, R. E. Vlietstra, D. R. Holmes, J. Am. Coll. Cardiol. 1992, 19, 267.
C. Indolfi, G. Esposito, E. Di Lorenzo, A. Rapacciuolo, A. Feliciello, A. Porcellini, V. E. Avvedimento, M. Condorelli, M. Chiariello, Circulation 1995, 92, 1230.
Y. Zhao, R. Du, T. Zhou, D. Yang, Y. Huang, Y. Wang, J. Huang, X. Ma, F. He, J. Qiu, G. Wang, Adv. Healthcare Mater. 2018, 7, 1800207.
J. M. Korde, B. Kandasubramanian, Biomater. Sci. 2018, 6, 1691.
J. Raymond, I. Salazkin, S. Georganos, F. Guilbert, A. C. Desfaits, G. Gevry, A. Weill, D. Roy, Am. J. Neuroradiol. 2002, 23, 1710.
R. Pinnaratip, M. S. A. Bhuiyan, K. Meyers, R. M. Rajachar, B. P. Lee, Adv. Healthcare Mater. 2019, 8, 1801568.
H. Heckroth CE, J. Hofmann, K. Lorenz (Medical Adhesys GmbH), EP 2794710 B1, 2014.
L. Xu, T. Zhang, H. Dong, D. Cai, H. Han, Q. Meng, Y. Tang, Q. Meng, Z. Gong, T. Zhang, Z. Zhang, H. Yan, K. Liu, J. Mater. Chem. B 2016, 4, 4147.
L. T E, Medical polymer adhesives. Biopolymers/Non-Exclusion HPLC. Advances in Polymer Science, Vol. 79, Springer, Berlin 1986.
M. Cabanlit, D. Maitland, T. Wilson, S. Simon, T. Wun, M. E. Gershwin, J. Van De Water, Macromol. Biosci. 2007, 7, 48.
J. Li, Z. Chen, X. Yang, Macromol. Biosci. 2019, 19, 1800482.
W.-C. Lin, C.-H. Tseng, M.-C. Yang, Macromol. Biosci. 2005, 5, 1013.
Y. Hong, F. Zhou, Y. Hua, X. Zhang, C. Ni, D. Pan, Y. Zhang, D. Jiang, L. Yang, Q. Lin, Y. Zou, D. Yu, D. E. Arnot, X. Zou, L. Zhu, S. Zhang, H. Ouyang, Nat. Commun. 2019, 10, 2060.
J. S. Lee, J. P. Kim, J. S. Ryu, S. H. Woo, Surgery 2018, 164, 965.
H. A. Kayaoglu, O. F. Ersoy, N. Ozkan, A. Celik, N. O. Filiz, Kaohsiung J. Med. Sci. 2009, 25, 177.
J. M. Reinke, H. Sorg, Eur. Surg. Res. 2012, 49, 35.
H. Heckroth CEMAG, EP 2699614 B1, 2015.
T. Mücke, K.-D. Wolff, S. Wagenpfeil, F. Hölzle, M. Scholz, Plast. Reconstr. Surg. 2010, 126, 1506.
A. Raabe, J. Beck, R. Gerlach, M. Zimmermann, V. Seifert, Neurosurgery 2003, 52, 132.
T. Binder, H. Diem, R. Fuchs, K. Gutensohn, T. Nebe, J. Lab. Med. 2012, 36, 293.
K. Donath, G. Breuner, J. Oral Pathol. 1982, 11, 318.
M. Scholz, T. Mücke, M. V. Düring, I. Pechlivanis, K. Schmieder, A. Harders, Minimally Invasive Neurosurg. 2008, 51, 76.