The X chromosome from telomere to telomere: key achievements and future opportunities.
CpG islands
DNA methylation
High-coverage sequencing
Human X chromosome
Telomere
Journal
Faculty reviews
ISSN: 2732-432X
Titre abrégé: Fac Rev
Pays: England
ID NLM: 101769226
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
28
1
2022
pubmed:
29
1
2022
medline:
29
1
2022
Statut:
epublish
Résumé
While the human genome represents the most accurate vertebrate reference assembly to date, it still contains numerous gaps, including centromeric and other large repeat-containing regions - often termed the "dark side" of the genome - many of which are of fundamental biological importance. Miga
Identifiants
pubmed: 35088059
doi: 10.12703/r-01-000001
pmc: PMC8753988
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
63Informations de copyright
Copyright: © 2021 Faculty Opinions Ltd.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Nat Biotechnol. 2018 Apr;36(4):338-345
pubmed: 29431738
Nat Biotechnol. 2019 Oct;37(10):1155-1162
pubmed: 31406327
Nature. 2020 Sep;585(7823):79-84
pubmed: 32663838
Nat Biotechnol. 2021 Mar;39(3):302-308
pubmed: 33288906