Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
28 Jan 2022
Historique:
entrez: 28 1 2022
pubmed: 29 1 2022
medline: 29 1 2022
Statut: ppublish

Résumé

c-Myc (hereafter, Myc) is a cancer driver whose abundance is regulated by the SCF

Identifiants

pubmed: 35089787
doi: 10.1126/sciadv.abl7872
pmc: PMC8797792
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabl7872

Subventions

Organisme : NCI NIH HHS
ID : P30 CA015704
Pays : United States
Organisme : NIH HHS
ID : S10 OD023476
Pays : United States

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Auteurs

Markus Welcker (M)

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Baiyun Wang (B)

Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

Domniţa-Valeria Rusnac (DV)

Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

Yasser Hussaini (Y)

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Jherek Swanger (J)

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Ning Zheng (N)

Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.
Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

Bruce E Clurman (BE)

Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Classifications MeSH