Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle.
actin
cardiac muscle
deoxy-ATP
induced pluripotent stem cells (iPSC)
mavacamten
myofibrils
myosin
myosin filament
regulation
skeletal muscle
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
15
11
2021
revised:
21
01
2022
accepted:
23
01
2022
pubmed:
30
1
2022
medline:
16
4
2022
entrez:
29
1
2022
Statut:
ppublish
Résumé
Muscle myosin heads, in the absence of actin, have been shown to exist in two states, the relaxed (turnover ∼0.05 s
Identifiants
pubmed: 35090895
pii: S0021-9258(22)00080-1
doi: 10.1016/j.jbc.2022.101640
pmc: PMC8867123
pii:
doi:
Substances chimiques
Adenosine Triphosphate
8L70Q75FXE
Myosins
EC 3.6.4.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101640Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL128368
Pays : United States
Organisme : NIGMS NIH HHS
ID : RM1 GM131981
Pays : United States
Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest This article reflects only the authors' view. The European Commission is not responsible for any use that may be made of the information it contains.