Consideration of the Optimal Surgical Procedure Based on the Risk of Recurrence in Clinical Stage 0 or IA Lung Adenocarcinoma.
Lung adenocarcinoma
TNM staging
recurrence
surgical resection
Journal
Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
16
12
2021
revised:
06
01
2022
accepted:
10
01
2022
entrez:
30
1
2022
pubmed:
31
1
2022
medline:
5
2
2022
Statut:
ppublish
Résumé
Sublobar resection is widely performed for early-stage non-small cell lung cancer in the clinical setting. This study evaluated the optimal surgical procedures of clinical stage 0 or IA adenocarcinoma from the perspective of recurrence. A total of 508 lung adenocarcinoma patients diagnosed as c-stage 0 or IA were retrospectively investigated. The types of surgical procedures were lobectomy (n=328), segmentectomy (n=73), and wedge resection (n=107). Clinical T descriptors were cTis in 74, cT1mi in 68, cT1a in 94, cT1b in 181 and cT1c in 91 patients. Recurrence was observed in 46 cases (9%), including 3 (3.1%) with cT1a, 23 (12.7%) with cT1b and 20 (22.0%) with cT1c. The patients who received sublobar resection developed recurrence more often than the patients who received lobectomy among cT1b cases (10.1% vs. 21.4%) and cT1c cases (18.0% vs. 46.2%) (p=0.053 and p=0.023). The cT1b and cT1c cases should be considered for lobectomy to prevent recurrence.
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
Sublobar resection is widely performed for early-stage non-small cell lung cancer in the clinical setting. This study evaluated the optimal surgical procedures of clinical stage 0 or IA adenocarcinoma from the perspective of recurrence.
PATIENTS AND METHODS
METHODS
A total of 508 lung adenocarcinoma patients diagnosed as c-stage 0 or IA were retrospectively investigated.
RESULTS
RESULTS
The types of surgical procedures were lobectomy (n=328), segmentectomy (n=73), and wedge resection (n=107). Clinical T descriptors were cTis in 74, cT1mi in 68, cT1a in 94, cT1b in 181 and cT1c in 91 patients. Recurrence was observed in 46 cases (9%), including 3 (3.1%) with cT1a, 23 (12.7%) with cT1b and 20 (22.0%) with cT1c. The patients who received sublobar resection developed recurrence more often than the patients who received lobectomy among cT1b cases (10.1% vs. 21.4%) and cT1c cases (18.0% vs. 46.2%) (p=0.053 and p=0.023).
CONCLUSION
CONCLUSIONS
The cT1b and cT1c cases should be considered for lobectomy to prevent recurrence.
Identifiants
pubmed: 35093917
pii: 42/2/1137
doi: 10.21873/anticanres.15577
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1137-1142Informations de copyright
Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.