Urinary tract infections in children: clinical and antimicrobial resistance data from Bucharest area, Romania.
E. coli.
Urinary tract infections
antimicrobial resistance
children
Journal
Germs
ISSN: 2248-2997
Titre abrégé: Germs
Pays: Romania
ID NLM: 101596099
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
07
11
2021
revised:
28
11
2021
accepted:
29
11
2021
entrez:
31
1
2022
pubmed:
1
2
2022
medline:
1
2
2022
Statut:
epublish
Résumé
Urinary tract infections (UTIs) are among the most common bacterial diseases of childhood with an increased frequency in infants and young children. We conducted a retrospective study of children diagnosed with UTI in the Alessandrescu-Rusescu National Institute for Mother and Child Health, Bucharest, Romania between January 2017 and December 2019. We evaluated the patients' clinical characteristics, laboratory parameters and the resistance profile of the identified uropathogens. A total of 264 children were included in the analysis. Females (71.6%, n=186) and infants (52.7%, n=139) were more commonly affected. The recurrence rate was 27.7% and was positively associated with the presence of renal malformations. Age under 1-year, increased leukocyte and neutrophil counts, and elevated C-reactive protein were associated with hospitalization. We identified an increased resistance of uropathogens to antimicrobials commonly used in children. Reporting antimicrobial resistance from real-world clinical practice is necessary for accurate mapping and continuous updating of initial treatment recommendations until antibiogram results are received. In Romania and other countries, extensive studies are needed to follow up uropathogen resistance in both children and adults.
Identifiants
pubmed: 35096675
doi: 10.18683/germs.2021.1293
pii: germs.2021.1293
pmc: PMC8789350
doi:
Types de publication
Journal Article
Langues
eng
Pagination
583-591Informations de copyright
GERMS.
Déclaration de conflit d'intérêts
Conflicts of interest: All authors – none to declare.
Références
Germs. 2021 Jun 2;11(2):163-178
pubmed: 34422689
Eur J Clin Microbiol Infect Dis. 2019 Nov;38(11):2151-2158
pubmed: 31440915
Germs. 2021 Jun 2;11(2):199-210
pubmed: 34422692
Children (Basel). 2021 Jul 08;8(7):
pubmed: 34356564
Exp Ther Med. 2021 Jul;22(1):748
pubmed: 34055063
Germs. 2019 Mar 01;9(1):17-27
pubmed: 31119113
BMJ Paediatr Open. 2019 Sep 24;3(1):e000487
pubmed: 31646191
BMJ Clin Evid. 2015 Jun 12;2015:
pubmed: 26067232
Pediatr Infect Dis J. 2014 Jun;33(6):595-9
pubmed: 24326416
Recent Pat Inflamm Allergy Drug Discov. 2019;13(1):2-18
pubmed: 30592257
Eur J Pediatr. 2021 Sep 14;:
pubmed: 34519852
Antibiotics (Basel). 2021 May 02;10(5):
pubmed: 34063317