Effects of cognitive rehabilitation in Parkinson disease: a meta-analysis.
Cognitive impairment
Cognitive rehabilitation
Meta-analysis
Parkinson’s disease
Journal
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
18
10
2021
accepted:
19
11
2021
pubmed:
1
2
2022
medline:
16
3
2022
entrez:
31
1
2022
Statut:
ppublish
Résumé
Cognitive symptoms are common in Parkinson's disease (PD) and affect patients' quality of life. Pharmacological interventions often do not improve such deficits that might benefit of cognitive rehabilitation. However, previous meta-analysis on this topic reported inconsistent results. Clarifying the efficacy of cognitive rehabilitation would be pivotal to optimize treatment and reduce care's costs. This meta-analysis aims at determining whether current literature lays in favor of the effectiveness of cognitive rehabilitation in PD and at understanding whether its effect might change depending on the trained cognitive domain. We searched online databases for studies concerning cognitive rehabilitation in PD. Fourteen studies encompassing 767 participants were included. Analyses were conducted for each cognitive domain separately, examining several neuropsychological measures for each function. We found that rehabilitation improves global cognition, executive functions, and long- and short-term memory. The current body of research indicates that cognitive rehabilitation improves specific cognitive deficits in PD and that it should be tailored on patients' specific impairments. These interventions should be employed considering that not all the cognitive domains might benefit of a cognitive training. Finally, the high heterogeneity among studies suggests the need for more controlled clinical trials.
Sections du résumé
BACKGROUND AND OBJECTIVES
OBJECTIVE
Cognitive symptoms are common in Parkinson's disease (PD) and affect patients' quality of life. Pharmacological interventions often do not improve such deficits that might benefit of cognitive rehabilitation. However, previous meta-analysis on this topic reported inconsistent results. Clarifying the efficacy of cognitive rehabilitation would be pivotal to optimize treatment and reduce care's costs. This meta-analysis aims at determining whether current literature lays in favor of the effectiveness of cognitive rehabilitation in PD and at understanding whether its effect might change depending on the trained cognitive domain.
METHODS
METHODS
We searched online databases for studies concerning cognitive rehabilitation in PD. Fourteen studies encompassing 767 participants were included. Analyses were conducted for each cognitive domain separately, examining several neuropsychological measures for each function.
RESULTS
RESULTS
We found that rehabilitation improves global cognition, executive functions, and long- and short-term memory.
CONCLUSION
CONCLUSIONS
The current body of research indicates that cognitive rehabilitation improves specific cognitive deficits in PD and that it should be tailored on patients' specific impairments. These interventions should be employed considering that not all the cognitive domains might benefit of a cognitive training. Finally, the high heterogeneity among studies suggests the need for more controlled clinical trials.
Identifiants
pubmed: 35098360
doi: 10.1007/s10072-021-05772-4
pii: 10.1007/s10072-021-05772-4
doi:
Types de publication
Journal Article
Meta-Analysis
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2323-2337Subventions
Organisme : Ministero della Salute
ID : GR-2018-12367927
Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2021. Fondazione Società Italiana di Neurologia.
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