Can we identify hereditary TTR amyloidosis by the screening of carpal tunnel syndrome patients?
Amyloidosis
Carpal tunnel syndrome
Early diagnosis
TTR
Journal
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175
Informations de publication
Date de publication:
May 2022
May 2022
Historique:
received:
01
12
2021
accepted:
20
12
2021
pubmed:
1
2
2022
medline:
22
4
2022
entrez:
31
1
2022
Statut:
ppublish
Résumé
Hereditary TTR amyloidosis (ATTRv) is a progressive e disabling disease, leading to a gradual loss of ambulation and death. In the last decade, new treatments have drastically revolutionized natural history of disease, and they are more efficacious if precociously administered. However, diagnostic delay still represents an important challenge to resolve. We reported a case of two asymptomatic brothers that received a very precocious diagnosis of ATTRv thanks to the diagnosis of carpal tunnel syndrome. We proposed screening of the well-defined carpal tunnel syndrome to detect patients with ATTRv in a pre-symptomatic stage.
Identifiants
pubmed: 35098361
doi: 10.1007/s10072-021-05851-6
pii: 10.1007/s10072-021-05851-6
doi:
Substances chimiques
Prealbumin
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3435-3438Informations de copyright
© 2021. Fondazione Società Italiana di Neurologia.
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