Oral frailty and carriage of oral Candida in community-dwelling older adults (Check-up to discover Health with Energy for senior Residents in Iwamizawa; CHEER Iwamizawa).
Candida albicans
Candida glabrata
community-dwelling older adults
cross-sectional study
internal transcribed spacer 2
oral frailty
Journal
Gerodontology
ISSN: 1741-2358
Titre abrégé: Gerodontology
Pays: England
ID NLM: 8215850
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
revised:
14
12
2021
received:
11
05
2021
accepted:
16
01
2022
pubmed:
1
2
2022
medline:
23
2
2022
entrez:
31
1
2022
Statut:
ppublish
Résumé
To examine the association between oral frailty and oral Candida carriage as a general indicator of deteriorating oral function in older adults. Older adults exhibit an elevated risk of oral candidiasis caused by Candida. Although many studies have identified factors associated with oral Candida carriage, none have evaluated its relationship with oral function. This study included 210 community-dwelling older adults aged ≥60 years who participated in wellness checks. Fungal flora expression in saliva samples was evaluated to identify oral C. albicans and C. glabrata. Participants were categorised by detection of neither strain (group 1), either one of the strains (group 2), or both strains (group 3). The relationship between oral Candida carriage and oral frailty was evaluated by multinomial logistic regression analysis. The participants included 58 men and 152 women with a mean age of 74.2 ± 6.1 years. A total of 88 (41.9%), 94 (44.8%) and 28 (13.3%) participants were assigned to groups 1, 2 and 3 respectively. In the multinomial logistic regression analysis, significant associations were observed between group 1 and group 2 for "Have you choked on your tea or soup recently?" and the number of applicable oral frailty items. Between group 1 and group 3, significant associations were observed for the number of remaining teeth, masticatory performance and the number of applicable oral frailty items. We obtained basic data useful for intervention studies aimed at verifying whether oral function management prevents deterioration of the oral bacterial flora.
Sections du résumé
OBJECTIVE
OBJECTIVE
To examine the association between oral frailty and oral Candida carriage as a general indicator of deteriorating oral function in older adults.
BACKGROUND
BACKGROUND
Older adults exhibit an elevated risk of oral candidiasis caused by Candida. Although many studies have identified factors associated with oral Candida carriage, none have evaluated its relationship with oral function.
MATERIALS AND METHODS
METHODS
This study included 210 community-dwelling older adults aged ≥60 years who participated in wellness checks. Fungal flora expression in saliva samples was evaluated to identify oral C. albicans and C. glabrata. Participants were categorised by detection of neither strain (group 1), either one of the strains (group 2), or both strains (group 3). The relationship between oral Candida carriage and oral frailty was evaluated by multinomial logistic regression analysis.
RESULTS
RESULTS
The participants included 58 men and 152 women with a mean age of 74.2 ± 6.1 years. A total of 88 (41.9%), 94 (44.8%) and 28 (13.3%) participants were assigned to groups 1, 2 and 3 respectively. In the multinomial logistic regression analysis, significant associations were observed between group 1 and group 2 for "Have you choked on your tea or soup recently?" and the number of applicable oral frailty items. Between group 1 and group 3, significant associations were observed for the number of remaining teeth, masticatory performance and the number of applicable oral frailty items.
CONCLUSION
CONCLUSIONS
We obtained basic data useful for intervention studies aimed at verifying whether oral function management prevents deterioration of the oral bacterial flora.
Types de publication
Journal Article
Langues
eng
Pagination
49-58Subventions
Organisme : Japan Science and Technology(JST) Agency Center of Innovation (COI) Program
ID : JPMJCE1301
Organisme : JSPS KAKENHI
ID : 20H03873
Organisme : JSPS KAKENHI
ID : 20H03899
Organisme : the Japan Ministry of Health, Labor and Welfare Administrative Promotion Policy Science Comprehensive Research
ID : 20AA2006
Informations de copyright
© 2022 Gerodontology Association and John Wiley & Sons Ltd.
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