Preprocedural transthoracic Doppler echocardiography to identify stenosis associated with increased coronary flow after revascularisation.
Aged
Blood Flow Velocity
Coronary Stenosis
/ diagnostic imaging
Coronary Vessels
/ diagnostic imaging
Echocardiography, Doppler, Color
Female
Fractional Flow Reserve, Myocardial
Humans
Hyperemia
/ physiopathology
Male
Middle Aged
Percutaneous Coronary Intervention
/ adverse effects
Predictive Value of Tests
Prospective Studies
Recovery of Function
Severity of Illness Index
Treatment Outcome
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
31 01 2022
31 01 2022
Historique:
received:
28
08
2021
accepted:
17
01
2022
entrez:
1
2
2022
pubmed:
2
2
2022
medline:
17
3
2022
Statut:
epublish
Résumé
The benefit of percutaneous coronary intervention (PCI) has been reported to be associated with functional stenosis severity defined by fractional flow reserve (FFR). This study aimed to investigate the predictive ability of preprocedural transthoracic Doppler echocardiography (TDE) for increased coronary flow. A total of 50 left anterior descending arteries (LAD) that underwent TDE examinations were analysed. Hyperaemic LAD diastolic peak velocity (hDPV) was used as a surrogate of volumetric coronary flow. The increase in coronary flow was evaluated by the metric of % hDPV-increase defined by 100× (post-PCI hDPV-pre-PCI hDPV)/pre-PCI hDPV. The two groups divided by the median value of % hDPV-increase were compared, and the determinants of a significant coronary flow increase defined as more than the median % hDPV-increase were explored. After PCI, FFR values improved in all cases. hDPV significantly increased from 53.0 to 76.0 mm/s (P < 0.01) and the median % hDPV-increase was 45%, while hDPV decreased in 10 patients. On multivariable analysis, pre-PCI FFR and hDPV were independent predictors of a significant coronary flow increase. Preprocedural TDE-derived hDPV provided significant improvement of identification of lesions that benefit from revascularisation with respect to significant coronary flow increase.
Identifiants
pubmed: 35102261
doi: 10.1038/s41598-022-05683-0
pii: 10.1038/s41598-022-05683-0
pmc: PMC8803832
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1667Informations de copyright
© 2022. The Author(s).
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